Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4986121 | 1.00 | TSHR (0.30) | — | |
| Hydrochloric Acid SCHEMBL10842729 | 1.00 | — | — | |
| SCHEMBL97177 | 0.93 | — | — | |
| Bromide SCHEMBL10984057 | 0.86 | — | — | |
| SCHEMBL21179486 | 0.86 | TSHR (0.30) | — | |
| Iodide SCHEMBL8858866 | 0.86 | — | — | |
| SCHEMBL2141485 | 0.86 | TSHR (0.30) | — | |
| SCHEMBL10990883 | 0.86 | — | — | |
| SCHEMBL635877 | 0.86 | TSHR (0.30) | — | |
| SCHEMBL337916 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567511-A | Complex, complex catalyst, and preparation method and application thereof | 合肥中科科乐新材料有限责任公司 | 2024-02-20 | — | — | CN | claimed |
| CN-116535754-B | High-flame-retardance low-resistance fire-fighting tire and manufacturing process thereof | 山东华盛橡胶有限公司 | 2024-01-02 | — | — | CN | claimed |
| CN-116535754-A | High-flame-retardance low-resistance fire-fighting tire and manufacturing process thereof | 山东华盛橡胶有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-116478209-A | Imine type nitrogen-phosphine ligand, preparation method thereof and application thereof in hydroformylation reaction of olefin | 万华化学集团股份有限公司 | 2023-07-25 | — | — | CN | claimed |
| CN-115124569-B | Preparation method of chiral amino phosphine boron complex | 江苏欣诺科催化剂股份有限公司 | 2022-12-13 | — | — | CN | claimed |
| CN-115124569-A | Preparation method of chiral amino phosphine boron complex | 江苏欣诺科催化剂股份有限公司 | 2022-09-30 | — | — | CN | claimed |
| CN-109651435-B | Bipolar organic photoelectric functional material and preparation method thereof | 南京邮电大学 | 2020-10-16 | — | — | CN | claimed |
| CN-111763229-A | Preparation method of 6N electronic grade tert-butyl phosphine | 江苏南大光电材料股份有限公司 | 2020-10-13 | — | — | CN | claimed |
| CN-108409784-B | Preparation method of phosphorus chiral important intermediate | 上海交通大学 | 2020-07-14 | — | — | CN | claimed |
| CN-119998304-A | Compound, metal complex, catalyst composition for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer | 三菱化学株式会社 | 2025-05-13 | — | — | CN | disclosed |
| CN-117700459-B | Synthesis method and application of benzo five-membered C-P ring skeleton monophosphine ligand | 内蒙古大学 | 2024-11-08 | — | — | CN | disclosed |
| CN-118894883-A | Organic thiophosphine compound and synthesis method thereof | 中科纯萃科技(北京)有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-118878581-A | Indolyl-containing biphosphine ligand, and preparation method and application thereof | 中海石油炼化有限责任公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-118834236-A | Method for constructing P-chiral phosphonamide compound by nickel catalysis | 扬州大学 | 2024-10-25 | — | — | CN | disclosed |
| CN-109096338-B | Benzaphosphepillocenyl phosphine oxide ligand, complex containing same, preparation method and application | 中国科学院上海有机化学研究所 | 2020-05-12 | — | — | CN | disclosed |
| US-7414156-B2 | Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation | WARNER LAMBERT CO. (US) | 2008-08-19 | — | — | US | disclosed |
| US-20050124830-A1 | Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation | HOGE GARRETT S II (US) | 2005-06-09 | — | — | US | disclosed |
| US-6855849-B2 | Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation | WARNER-LAMBERT COMPANY (US) | 2005-02-15 | — | — | US | disclosed |
| CN-1445233-A | ALkyl VA group metal compound | HIPREY CORP (US) | 2003-10-01 | — | — | CN | disclosed |
| US-20030073868-A1 | Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation | WARNER-LAMBERT COMPANY | 2003-04-17 | — | — | US | disclosed |