Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | MMP16 | P51512 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3379318 | 1.00 | TP53 (0.38) | TP53SLC7A5ADAMTS4GABRR1LMNA | |
| SCHEMBL3380094 | 0.81 | TP53 (0.36) | TP53SLC7A5ADAMTS4GABRR1LMNA | |
| SCHEMBL3380093 | 0.81 | TP53 (0.36) | TP53SLC7A5ADAMTS4GABRR1LMNA | |
| SCHEMBL3379632 | 0.81 | TP53 (0.43) | TP53SLC7A5LMNA | |
| SCHEMBL17951879 | 0.81 | ADAMTS4 (0.37) | TP53SLC7A5ADAMTS4GABRR1LMNA | |
| SCHEMBL3379637 | 0.81 | TP53 (0.43) | TP53SLC7A5LMNA | |
| SCHEMBL3381142 | 0.75 | ALDH1A1 (0.38) | TP53ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3381140 | 0.75 | ALDH1A1 (0.38) | TP53ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL214942 | 0.74 | TP53 (0.40) | TP53SLC7A5ADAMTS4GABRR1MMP2 | |
| SCHEMBL14890392 | 0.74 | TP53 (0.40) | TP53SLC7A5ADAMTS4GABRR1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057444-B1 | DICHLOROAMINO ACID DERIVATIVES USEFUL AS POTENT GERMICIDAL AND FUNGICIDAL AGENTS | MERCK & CO. INC. (US) | 1986-05-07 | — | — | EP | claimed |
| US-4386103-A | ENVIRONMENT, FOOD TREATMENT, PERSONAL OR VETERINARY HYGIENE | MERCK & CO., INC. (US) | 1983-05-31 | — | — | US | claimed |
| EP-0057444-A2 | Dichloroamino acid derivatives useful as potent germicidal and fungicidal agents | MERCK & CO. INC. (US) | 1982-08-11 | — | — | EP | claimed |
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | disclosed |
| EP-2120555-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | Heller, Adam (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008094664-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2008-08-07 | — | — | WO | disclosed |
| US-4015008-A | N,N-dichloro substituted aminocarboxylic acids as microbiocides | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |
| US-3950536-A | N,N-Dichloro substituted aminocarboxylic acids as bactericides and fungicides | BARER SOL JOSEPH | 1976-04-13 | — | — | US | disclosed |