Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Salicyladehyde. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.78 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.78 |
| ▸ | ERN1 | O75460 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
| ▸ | CCND1 | P24385 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicyladehyde SCHEMBL531267 | 1.00 | TRIM24 (0.78) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL28464166 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL28410156 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL28374710 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL8857189 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL28369556 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL28961727 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL10486499 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL28454832 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL29091716 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117339621-A | Catalyst for preparing 2, 5-furandimethanol, preparation method and application | 中国石油化工股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-114292300-B | Spirobroma dihydrobenzosilol phosphonic acid monoester compound, preparation and application thereof | 中国科学院上海有机化学研究所 | 2023-09-15 | — | — | CN | claimed |
| CN-115287780-A | Lignocellulose-based intelligent color-changing composite fiber material and preparation method thereof | 北华大学 | 2022-11-04 | — | — | CN | claimed |
| CN-109983613-B | Electrode assembly, method of manufacturing the same, and secondary battery including the same | 株式会社LG化学 | 2022-06-07 | — | — | CN | claimed |
| CN-105037405-B | A kind of single molecular magnetses Dy2(salen)2(tta)4(OAc)2Preparation method | 黑龙江大学 | 2017-03-01 | — | — | CN | claimed |
| CN-103219148-B | A kind of preparation method of single molecular magnets | HEILONGJIANG UNIVERSITY (CN) | 2015-08-19 | — | — | CN | claimed |
| CN-103219148-A | Preparation method of single-molecule magnetic body | UNIV HEILONGJIANG | 2013-07-24 | — | — | CN | claimed |
| CN-103111373-A | Preparation method of ethanediamine shrinkage salicylaldehyde Schiff base chelate flotation agent | XUZHOU KAIMIKE NEW MATERIAL CO LTD | 2013-05-22 | — | — | CN | claimed |
| EP-1547105-A1 | ELECTROCHEMICAL CAPACITOR AND METHOD OF USE | Gen3 Partners, Inc. (US) | 2005-06-29 | — | — | EP | claimed |
| WO-2004032162-A1 | ELECTROCHEMICAL CAPACITOR AND METHOD OF USE | GEN3 PARTNERS, INC (US) | 2004-04-15 | — | — | WO | claimed |
| US-6392093-B1 | USING OXIDATION CATALYST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2002-05-21 | — | — | US | claimed |
| JP-60063465-A | — | — | None | — | — | JP | disclosed |
| JP-56118063-A | — | — | None | — | — | JP | disclosed |
| CN-117825469-B | Ag/AgCl reference electrode composition and Ag/AgCl reference electrode and application | 乐普（北京）医疗器械股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-117858692-A | Improved compositions and methods for styling hair fibers | 兰达实验室（2012）有限公司 | 2024-04-09 | — | — | CN | disclosed |
| US-4338291-A | Process for producing hydrogen with viologen cation radical using metal complex of macrocyclic polydentate compound as catalyst | RIKAGAKU KENKYUSHO (JP) | 1982-07-06 | — | — | US | disclosed |
| JP-S56118063-A | PREPARATION OF VIOLOGEN CATION RADICAL USING CYCLIC MULTIDENTATE LIGAND METAL COMPLEX | RIKAGAKU KENKYUSHO | 1981-09-16 | — | — | JP | disclosed |
| US-4087256-A | REACTING ALPHATIC POLYAMINE WITH BETA-DIKETONE, REACTING RESULTING PRODUCT WITH SALICYLALDEHYDE, PREVENTING OXIDATIVE DEGRADATION OR COPPER-MERCAPTAN GELATION | ASHLAND OIL, INC. (US) | 1978-05-02 | — | — | US | disclosed |
| US-4065498-A | REACTING 1,2-ALKANEDIAMINE AND A 2,4-DIONE | ASHLAND OIL, INC. (US) | 1977-12-27 | — | — | US | disclosed |
| US-4022835-A | ALIPHATIC POLYAMINES, BETA-DIKETONE, SALICYLALDEHYDE | ASHLAND OIL, INC. (US) | 1977-05-10 | — | — | US | disclosed |