Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Salicyladehyde. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.78 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.78 |
| ▸ | ERN1 | O75460 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
| ▸ | CCND1 | P24385 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicyladehyde SCHEMBL3379351 | 1.00 | TRIM24 (0.78) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL28464166 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL28410156 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL28374710 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL8857189 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL28369556 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL28961727 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL10486499 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL28454832 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 | |
| Salicyladehyde SCHEMBL29091716 | 0.98 | TRIM24 (0.75) | TRIM24TRIM33ERN1LMNACDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12381231-B2 | Cathode for metal-air current sources and metal-air current source with such cathode | POWERMERS SMART INDUSTRIES INC. (US) | 2025-08-05 | — | — | US | claimed |
| CN-114195634-B | Preparation method of 2-biphenyl propionic acid compound | 上海惠永药物研究有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-117825469-A | Ag/AgCl reference electrode composition and Ag/AgCl reference electrode and application | 乐普（北京）医疗器械股份有限公司 | 2024-04-05 | — | — | CN | claimed |
| US-20230223553-A1 | CATHODE FOR METAL-AIR CURRENT SOURCES METAL-AIR CURRENT SOURCES CONTAINING THE SAME | POWERMERS INC. (US) | 2023-07-13 | — | — | US | claimed |
| CN-111909371-B | Tetraalkenyl polyphenyl ether and preparation method thereof | 广东省石油与精细化工研究院 | 2022-12-27 | — | — | CN | claimed |
| CN-111793203-B | Polyphenyl ether and synthesis method thereof | 广东省石油与精细化工研究院 | 2022-12-27 | — | — | CN | claimed |
| US-11482746-B2 | Cathode for metal-air current sources metal-air current sources containing the same | POWERMERS INC. (US) | 2022-10-25 | — | — | US | claimed |
| CN-114195634-A | Preparation method of 2-biphenylyl propionic acid compound | 上海惠永药物研究有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-110041222-B | Thymoquinone derivative, intermediate, preparation method and application thereof | 江苏耐雀生物工程技术有限公司 | 2022-02-25 | — | — | CN | claimed |
| CN-111234248-B | Method for synthesizing size-adjustable metal complex microspheres from Schiff base and metal complex microspheres | 安徽师范大学 | 2021-12-21 | — | — | CN | claimed |
| EP-0560910-B1 | MOLECULAR SIEVE-ENCLOSED PARAMAGNETIC ION FOR DIAGNOSIS | UNIV TEXAS (US) | 1996-03-13 | — | — | EP | claimed |
| EP-0646237-A4 | CLAY ENCLOSED TRANSITION AND RARE EARTH METAL IONS AS CONTRAST AGENTS FOR THE GASTROINTESTINAL TRACT. | UNIV TEXAS (US) | 1995-11-08 | — | — | EP | claimed |
| EP-0646237-A1 | CLAY ENCLOSED TRANSITION AND RARE EARTH METAL IONS AS CONTRAST AGENTS FOR THE GASTROINTESTINAL TRACT | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-04-05 | — | — | EP | claimed |
| EP-0502964-B1 | USE OF COMPLEX LIGANDS FOR IONS IN FERROELECTRIC LIQUID CRYSTAL MIXTURES | HOECHST AG (DE) | 1995-02-22 | — | — | EP | claimed |
| US-5277896-A | Paramagnetism | BOARD OF REAGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1994-01-11 | — | — | US | claimed |
| WO-1993025895-A1 | CLAY ENCLOSED TRANSITION AND RARE EARTH METAL IONS AS CONTRAST AGENTS FOR THE GASTROINTESTINAL TRACT | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1993-12-23 | — | — | WO | claimed |
| EP-0560910-A1 | MOLECULAR SIEVE-ENCLOSED PARAMAGNETIC ION FOR DIAGNOSIS. | UNIV TEXAS (US) | 1993-09-22 | — | — | EP | claimed |
| WO-1992010213-A1 | MOLECULAR SIEVE-ENCLOSED PARAMAGNETIC ION FOR DIAGNOSIS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-06-25 | — | — | WO | claimed |
| US-3965069-A | Polyphenylene oxide is prepared using a mixture of manganese chelates as a catalyst | GENERAL ELECTRIC COMPANY (US) | 1976-06-22 | — | — | US | claimed |
| US-3962250-A | OXIDATION PRODUCTS OF COBALT COMPLEXES, PROCESS FOR OBTAINING SAME AND INSERTION PROCESS | SNAM PROGETTI S.P.A. (IT) | 1976-06-08 | — | — | US | claimed |