Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.48 |
| ▸ | BRS3 | P32247 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10584394 | 0.84 | SHMT2 (0.47) | SHMT2BRS3KMT2AWDR5HPGD | |
| SCHEMBL14356330 | 0.81 | HPGD (0.48) | SHMT2BRS3KMT2AWDR5HTT | |
| SCHEMBL20387986 | 0.79 | SHMT2 (0.42) | SHMT2BRS3KMT2AWDR5ALDH1A1 | |
| SCHEMBL5197626 | 0.77 | KMT2A (0.41) | SHMT2BRS3KMT2AWDR5HTT | |
| SCHEMBL4958916 | 0.77 | KMT2A (0.41) | SHMT2BRS3KMT2AWDR5HTT | |
| Water SCHEMBL4555319 | 0.75 | KMT2A (0.40) | SHMT2BRS3KMT2AWDR5HTT | |
| SCHEMBL6474161 | 0.75 | SHMT2 (0.51) | SHMT2BRS3KMT2AWDR5HTT | |
| SCHEMBL10866252 | 0.74 | SHMT2 (0.49) | SHMT2BRS3KMT2AWDR5HTT | |
| SCHEMBL10578851 | 0.74 | BRS3 (0.74) | SHMT2BRS3KMT2AWDR5HTT | |
| SCHEMBL10867894 | 0.74 | SHMT2 (0.72) | SHMT2BRS3KMT2AWDR5HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773940-B2 | PROCESS FOR SYNTHESIS OF SUBSTITUTED SULPHOXIDES | ASTRAZENECA AB (SE) | 2010-11-17 | — | — | EP | disclosed |
| EP-2106397-A1 | A PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE ESOMEPRAZOLE | Hetero Drugs Limited (IN) | 2009-10-07 | — | — | EP | disclosed |
| WO-2009040825-A1 | A PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE ESOMEPRAZOLE | HETERO DRUGS LIMITED (IN) | 2009-04-02 | — | — | WO | disclosed |
| EP-0773940-B1 | PROCESS FOR SYNTHESIS OF SUBSTITUTED SULPHOXIDES | ASTRAZENECA AB (SE) | 2003-06-04 | — | — | EP | disclosed |