Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | BRS3 | P32247 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474161 | 0.76 | SHMT2 (0.51) | SHMT2ALDH1A1MAPTHSD17B10KMT2A | |
| SCHEMBL10867601 | 0.75 | KMT2A (0.43) | SHMT2ALDH1A1MAPTHSD17B10KMT2A | |
| SCHEMBL10867894 | 0.74 | SHMT2 (0.72) | SHMT2ALDH1A1MAPTHSD17B10MAPK1 | |
| SCHEMBL10578851 | 0.74 | BRS3 (0.74) | SHMT2MAPTKMT2AMEN1BRS3 | |
| SCHEMBL3379391 | 0.74 | SHMT2 (0.48) | SHMT2ALDH1A1MAPTTSHRKMT2A | |
| SCHEMBL8500397 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPTHSD17B10MAPK1TSHR | |
| SCHEMBL141138 | 0.73 | ALDH1A1 (0.70) | ALDH1A1MAPTHSD17B10MAPK1TSHR | |
| SCHEMBL18443070 | 0.72 | ELANE (0.56) | ALDH1A1MAPTHSD17B10MAPK1TSHR | |
| SCHEMBL25538982 | 0.72 | MAPK1 (0.58) | ALDH1A1MAPTHSD17B10MAPK1TSHR | |
| SCHEMBL10584394 | 0.72 | SHMT2 (0.47) | SHMT2MAPTHSD17B10KMT2ABRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174717-A1 | Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1986-03-19 | — | — | EP | disclosed |