Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | SNCA | P37840 | 2/20 | 0.46 |
| ▸ | CASR | P41180 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6389232 | 0.83 | TSHR (0.55) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL9353883 | 0.82 | TSHR (0.53) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL5414637 | 0.80 | TSHR (0.52) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL8916275 | 0.80 | TSHR (0.52) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL25677850 | 0.80 | TSHR (0.52) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL3380651 | 0.80 | TSHR (0.52) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL29027899 | 0.80 | TSHR (0.52) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL393137 | 0.80 | TSHR (0.62) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL176757 | 0.80 | TSHR (0.52) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL11334838 | 0.78 | CA12 (0.65) | ALDH1A1CASRCA2CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | claimed |
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | disclosed |