Sugi Predict

Sugi Predict / Compounds / SCHEMBL393137

SCHEMBL393137

SCHEMBL393137

NNc1cccc(S(=O)(=O)O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.62
▸ ALDH1A1 P00352 2/20 0.62
▸ HSD17B10 Q99714 2/20 0.62
▸ TDP1 Q9NUW8 1/20 0.62
▸ CASR P41180 3/20 0.49
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ SNCA P37840 1/20 0.46
▸ CA2 P00918 6/20 0.45
▸ CA1 P00915 5/20 0.45
▸ CA12 O43570 4/20 0.45
▸ CA9 Q16790 4/20 0.45
▸ MAPT P10636 1/20 0.45
▸ POLB P06746 2/20 0.43
▸ HTR6 P50406 1/20 0.43
▸ NOS1 P29475 1/20 0.42
▸ LMNA P02545 2/20 0.41
▸ CA4 P22748 1/20 0.41
▸ CA6 P23280 1/20 0.41
▸ CA5A P35218 1/20 0.41
▸ CA7 P43166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL27953344 0.98 TSHR (0.60) TSHRALDH1A1HSD17B10TDP1CASR
SCHEMBL6389232 0.83 TSHR (0.55) TSHRALDH1A1HSD17B10TDP1CASR
SCHEMBL359584 0.82 CA2 (0.64) CA2CA1CA12CA9MAPT
SCHEMBL9353883 0.82 TSHR (0.53) TSHRALDH1A1HSD17B10TDP1CASR
Phenylhydrazine SCHEMBL7535360 0.80 CA1 (0.54) TSHRCA2CA1MAPTPOLB
SCHEMBL1117957 0.80 ROCK1 (0.51) ALDH1A1SMN1; SMN2CA2CA1CA12
Hydrochloric Acid SCHEMBL11777840 0.80 CA2 (0.61) CA2CA1CA12CA9MAPT
SCHEMBL3380651 0.80 TSHR (0.52) TSHRALDH1A1HSD17B10TDP1CASR
SCHEMBL3379465 0.80 TSHR (0.52) TSHRALDH1A1HSD17B10TDP1CASR
SCHEMBL176757 0.80 TSHR (0.52) TSHRALDH1A1HSD17B10TDP1CASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115210289-B Polyester resin and process for producing the same 尤尼吉可株式会社 2024-01-05 — — CN disclosed
US-20230089078-A1 POLYESTER RESIN AND PRODUCTION METHOD THEREFOR UNITIKA LTD. (JP) 2023-03-23 — — US disclosed
CN-115210289-A Polyester resin and method for producing same 尤尼吉可株式会社 2022-10-18 — — CN disclosed
US-11040938-B2 Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) 2021-06-22 — — US disclosed
CN-107663161-B Continuous flow synthesis process of phenylhydrazine salt and substituted phenylhydrazine salt 上海惠和化德生物科技有限公司 2020-04-10 — — CN disclosed
US-20190152896-A1 Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) 2019-05-23 — — US disclosed
CN-103275513-B Azo-compound and comprise dye-based polarizing film and the polaroid of described azo-compound NIPPON KAYAKU K. K. (JP) 2015-08-19 — — CN disclosed
CN-103592381-B Method for detecting sulfonic acid phenylhydrazine sulfate series by high performance liquid chromatography HUBEI SHENZHOU CHEMICAL CO LTD 2015-01-14 — — CN disclosed
CN-103592381-A Method for detecting sulfonic acid phenylhydrazine sulfate series by high performance liquid chromatography HUBEI SHENZHOU CHEMICAL CO LTD 2014-02-19 — — CN disclosed
US-8242278-B2 Process for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-14 — — US disclosed
US-5869516-A 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-02-09 — — US disclosed
CN-1141291-A 4-(Arylaminomethylene)-2,4-dihydro-3-pyrazolones MERCK PATENT GMBH (DE) 1997-01-29 — — CN disclosed
EP-0743304-A1 4-(Arylaminomethylene)-2,4-dihydro-pyrazol-3-ones MERCK PATENT GmbH (DE) 1996-11-20 — — EP disclosed
EP-0040745-B1 PROCESS FOR PREPARING V-TRIAZOLE COMPOUNDS BAYER AG (DE) 1984-09-26 — — EP disclosed
EP-0040357-B1 PROCESS FOR THE PREPARATION OF V-TRIAZOLYL-(2) PHENOLS BAYER AG (DE) 1984-09-19 — — EP disclosed
US-4347357-A Process for the preparation of v-triazole compounds BAYER AKTIENGESELLSCHAFT (DE) 1982-08-31 — — US disclosed
EP-0040745-A1 Process for preparing v-triazole compounds BAYER AG (DE) 1981-12-02 — — EP disclosed
EP-0040357-A1 Process for the preparation of v-triazolyl-(2) phenols BAYER AG (DE) 1981-11-25 — — EP disclosed
US-4045169-A FLUORESCENT DYES HOECHST AKTIENGESELLSCHAFT (DT) 1977-08-30 — — US disclosed
US-3957815-A 3-[3',4'-Dichloro-6'-alkyl-phenyl]-Δ2 -pyrazoline derivatives and their use as optical brighteners HOECHST AKTIENGESELLSCHAFT (DT) 1976-05-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11040938-B2 Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts HPD, TYR, PDK2 TSHR 3207/4885ALDH1A1 379/4885HSD17B10 1082/4885
US-20190152896-A1 Continuous Flow Process For the Synthesis of Phenylhydrazine Salts and Substituted Phenylhydrazine Salts HPD, TYR, PDK2 TSHR 3207/4885ALDH1A1 379/4885HSD17B10 1082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.