SCHEMBL3379723

SCHEMBL3379723

C=CC(=O)NCN(C)CCC(C)C

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
ALPL P05186 1/20 0.32
TGM2 P21980 1/20 0.31
HTT P42858 1/20 0.31
CHRNB2 P17787 1/20 0.30
CHRNB4 P30926 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18331599 0.81 TSHR (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL29208061 0.80 TSHR (0.43) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL20543334 0.79 ZDHHC20 (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL29207951 0.79 TSHR (0.46) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL28516947 0.76 ZDHHC20 (0.55) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL21143016 0.76 TSHR (0.41) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL28091336 0.75 TSHR (0.39) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL7595581 0.75 ALDH1A1 (0.50) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL410374 0.75 ZDHHC20 (0.52) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL420273 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110183571-B Paper strength enhancer and paper 播磨化成株式会社 2022-06-07 CN disclosed
CN-110003386-B Polyacrylamide resin, papermaking additive and paper 哈利玛化成株式会社 2021-10-15 CN disclosed
CN-110799704-B (meth) acrylamide polymer additive for papermaking and method for producing same 哈利玛化成株式会社 2020-12-01 CN disclosed
CN-110799704-A Method for producing (meth) acrylamide polymer additive for papermaking, and (meth) acrylamide polymer additive for papermaking 哈利玛化成株式会社 2020-02-14 CN disclosed
EP-1683645-B1 Method for making tinted optical lenses ESSILOR INT (FR) 2010-11-17 EP disclosed
CN-101119852-B Optical lens tinting method ESSILOR INT 2010-05-19 CN disclosed
US-20090047424-A1 INK RECEPTIVE MATERIAL, TINTED OPTICAL LENSES AND METHOD FOR MANUFACTURING THE SAME ESSILOR INTERNATIONAL/ NIKON-ESSILOR CO., LTD. (JP) 2009-02-19 US disclosed
CN-101119852-A Ink receptive material, tinted optical lenses and method for manufacturing the same ESSILOR INT (FR) 2008-02-06 CN disclosed
WO-2006079564-A1 INK RECEPTIVE MATERIAL, TINTED OPTICAL LENSES AND METHOD FOR MANUFACTURING THE SAME ESSILOR INTERNATIONAL (FR) 2006-08-03 WO disclosed
EP-1683645-A1 Tinted optical lenses and method for manufacturing the same ESSILOR INTERNATIONAL (Compagnie Générale d'Optique) (FR) 2006-07-26 EP disclosed
US-6541567-B1 Comprises anionic polyester in which hydrophilic vinylpyrrolidone has been graft-polymerized, and cationic polymer surrounded by polyvinyl alcohol; radiation transparency TAKAMATSU OIL & FAT CO., LTD. (JP) 2003-04-01 US disclosed
EP-0995609-A1 COATING COMPOSITION FOR INK RECEPTOR LAYER IMPROVED IN THE FIXATION OF INK AND WATER RESISTANCE, AND PROCESS FOR THE PREPARATION THEREOF Takamatsu Oil & Fat Co., Ltd (JP) 2000-04-26 EP disclosed