Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 2/20 | 0.48 |
| ▸ | GRM6 | O15303 | 2/20 | 0.48 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL3379835 | 1.00 | GRM8 (0.48) | GRM8GRM6GRM7GRM4GRIK1 | |
| Aspartic Acid SCHEMBL1891183 | 0.93 | GRM8 (0.47) | GRM8GRM6GRM7GRM4GRIK1 | |
| Aspartic Acid SCHEMBL1891184 | 0.93 | GRM8 (0.47) | GRM8GRM6GRM7GRM4GRIK1 | |
| Aspartic Acid SCHEMBL11300995 | 0.91 | SLC7A5 (0.48) | GRM8GRM6GRM7GRM4GRIK1 | |
| Aspartic Acid SCHEMBL3231 | 0.89 | — | — | |
| D-Aspartate SCHEMBL145539 | 0.89 | — | — | |
| Aspartic Acid SCHEMBL1526976 | 0.89 | GRIK1 (0.56) | GRM8GRM6GRM7GRM4GRIK1 | |
| Aspartic Acid SCHEMBL11065189 | 0.89 | GRIK1 (0.56) | GRM8GRM6GRM7GRM4GRIK1 | |
| Aspartic Acid SCHEMBL11065185 | 0.89 | GRIK1 (0.56) | GRM8GRM6GRM7GRM4GRIK1 | |
| Aspartic Acid SCHEMBL996424 | 0.89 | GRIK1 (0.56) | GRM8GRM6GRM7GRM4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040763-A | Polyimide and polyvinyl alcohol composite material with random copolymerization and preparation method thereof | 常州大学 | 2025-05-27 | — | — | CN | claimed |
| CN-117024801-A | Preparation method of conductive flame-retardant double-property polyvinyl alcohol transparent film | 安徽理工大学环境友好材料与职业健康研究院(芜湖) | 2023-11-10 | — | — | CN | claimed |
| CN-120040763-A | Polyimide and polyvinyl alcohol composite material with random copolymerization and preparation method thereof | 常州大学 | 2025-05-27 | — | — | CN | disclosed |
| CN-118184831-A | Carbomer carrier structure polymer formed by carbomer and phosphoric acid amino acid, and preparation and application thereof | 吉林省远志医学科技有限公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2024011666-A1 | L-HOMOSERINE HIGH-YIELD STRAIN, CONSTRUCTION METHOD THEREFOR, AND USE THEREOF | 南京盛德生物科技研究院有限公司 | 2024-01-18 | — | — | WO | disclosed |
| CN-117024801-A | Preparation method of conductive flame-retardant double-property polyvinyl alcohol transparent film | 安徽理工大学环境友好材料与职业健康研究院(芜湖) | 2023-11-10 | — | — | CN | disclosed |
| CN-117024801-A | Preparation method of conductive flame-retardant double-property polyvinyl alcohol transparent film | 安徽理工大学环境友好材料与职业健康研究院(芜湖) | 2023-11-10 | — | — | CN | disclosed |
| CN-116286566-A | L-homoserine high-yield strain and construction method and application thereof | 南京盛德生物科技研究院有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-115725537-A | Aspartokinase mutant and application thereof in producing L-homoserine | 中国科学院天津工业生物技术研究所 | 2023-03-03 | — | — | CN | disclosed |
| CN-111607551-B | Method for producing aspartic acid, derivatives thereof and glutamic acid based on halophilic bacteria | 清华大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-113201514-B | Polypeptides having aspartokinase activity and their use for producing amino acids | 中国科学院天津工业生物技术研究所 | 2022-09-06 | — | — | CN | disclosed |
| WO-2007011939-A2 | USE OF DIMETHYL DISULFIDE FOR METHIONINE PRODUCTION IN MICROORGANISMS | BASF AG (DE) | 2007-01-25 | — | — | WO | disclosed |
| CN-1333361-A | Novel polypeptide--human L-3-phosphoserine phosphatase 10.01 and polynucleotide for encoding said polypeptide | BODE GENE DEV CO LTD SHANGHAI (CN) | 2002-01-30 | — | — | CN | disclosed |
| CN-1068351-C | Prepn. method and application of amino acid condensation polymers and their hydrolytic products | RHONE POULENC CHIMIE (FR) | 2001-07-11 | — | — | CN | disclosed |
| US-5824765-A | Preparation of polycondensates of amino acids and the biodegradable polypeptide hydrolysates thereof | RHONE-POULENC CHIMIE (FR) | 1998-10-20 | — | — | US | disclosed |
| US-5688903-A | Process for the preparation of polycondensates of amino acids and the biodegradable polypeptide hydrolysates thereof, and their use in detergent compositions | RHONE-POULENC CHIMIE (FR) | 1997-11-18 | — | — | US | disclosed |
| CN-1128771-A | Prepn. method and application of amino acid condensation polymers and their hydrolytic products | RHONE POULENC CHIMIE (FR) | 1996-08-14 | — | — | CN | disclosed |
| US-5009994-A | Uniform distribution | EM DIAGNOSTIC SYSTEMS, INC. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4820627-A | SPRAYING AQUEOUS SOLUTIONS OF LABILE BIOCHEMICALS ONTO BULKING AGENTS | EM DIAGNOSTIC SYSTEMS, INC. (US) | 1989-04-11 | — | — | US | disclosed |
| US-4390625-A | ERGOCORNINE AND ERGOCRYPTINE | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1983-06-28 | — | — | US | disclosed |