⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL735087 | 0.92 | ESR1 (0.38) | — | |
| SCHEMBL987593 | 0.92 | ESR1 (0.38) | — | |
| SCHEMBL1286045 | 0.92 | ESR1 (0.38) | — | |
| SCHEMBL16892538 | 0.92 | ESR1 (0.38) | — | |
| SCHEMBL1285757 | 0.92 | ESR1 (0.38) | — | |
| SCHEMBL131435 | 0.86 | — | — | |
| SCHEMBL16892561 | 0.82 | SIGMAR1 (0.47) | — | |
| SCHEMBL16892552 | 0.82 | ESR1 (0.36) | — | |
| SCHEMBL16892539 | 0.82 | SIGMAR1 (0.47) | — | |
| SCHEMBL16892585 | 0.79 | MEN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017027309-A1 | GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2017-02-16 | — | — | WO | claimed |
| EP-1165557-B1 | ARYL AND HETEROARYL FUSED AMINOALKYL-IMIDAZOLE DERIVATIVES: SELECTIVE MODULATORS OF GABAa RECEPTORS | NEUROGEN CORP (US) | 2004-09-29 | — | — | EP | claimed |
| US-6627624-B1 | Agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs of agonists, antagonists or inverse agonists for GABAa brain receptors, and are therefore useful in the diagnosis and treatment of anxiety, Down Syndrome, | NEUROGEN CORPORATION | 2003-09-30 | — | — | US | claimed |
| EP-3902023-B1 | COMPOSITION CONTAINING ORGANIC SEMICONDUCTOR, SOLUTION FOR FORMING ORGANIC SEMICONDUCTOR LAYER, ORGANIC SEMICONDUCTOR LAYER, AND ORGANIC THIN FILM TRANSISTOR | TOSOH CORP (JP) | 2024-04-24 | — | — | EP | disclosed |
| CN-113906059-B | Catalyst system | 博里利斯股份公司 | 2024-03-12 | — | — | CN | disclosed |
| US-20230142592-A1 | AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR LAYER AND ORGANIC THIN FILM TRANSISTOR | TOSOH CORPORATION (JP) | 2023-05-11 | — | — | US | disclosed |
| EP-4116304-A1 | AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR LAYER AND ORGANIC THIN FILM TRANSISTOR | Tosoh Corporation (JP) | 2023-01-11 | — | — | EP | disclosed |
| CN-115210239-A | Aromatic compound, organic semiconductor layer and organic thin film transistor | 东曹株式会社 | 2022-10-18 | — | — | CN | disclosed |
| US-20220059768-A1 | COMPOSITION CONTAINING ORGANIC SEMICONDUCTOR, SOLUTION FOR FORMING ORGANIC SEMICONDUCTOR LAYER, ORGANIC SEMICONDUCTOR LAYER, AND ORGANIC THIN FILM TRANSISTOR | TOSOH CORPORATION (JP) | 2022-02-24 | — | — | US | disclosed |
| CN-113906059-A | Catalyst system | 博里利斯股份公司 | 2022-01-07 | — | — | CN | disclosed |
| EP-3902023-A1 | COMPOSITION CONTAINING ORGANIC SEMICONDUCTOR, SOLUTION FOR FORMING ORGANIC SEMICONDUCTOR LAYER, ORGANIC SEMICONDUCTOR LAYER, AND ORGANIC THIN FILM TRANSISTOR | Tosoh Corporation (JP) | 2021-10-27 | — | — | EP | disclosed |
| WO-2004090094-A2 | L-CARNITIN DEHYDROGENASES, THEIR DERIVATIVES AND METHOD FOR PRODUCING SUBSTITUTED (S) ALKANOLS | BASF AKTIENGESELLSCHAFT (DE) | 2004-10-21 | — | — | WO | disclosed |
| EP-1165557-B1 | ARYL AND HETEROARYL FUSED AMINOALKYL-IMIDAZOLE DERIVATIVES: SELECTIVE MODULATORS OF GABAa RECEPTORS | NEUROGEN CORP (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6627624-B1 | Agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs of agonists, antagonists or inverse agonists for GABAa brain receptors, and are therefore useful in the diagnosis and treatment of anxiety, Down Syndrome, | NEUROGEN CORPORATION | 2003-09-30 | — | — | US | disclosed |
| US-6380210-B1 | USEFUL IN DIAGNOSIS AND TREATMENT OF ANXIETY, DOWN SYNDROME, SLEEP, COGNITIVE AND SEIZURE DISORDERS, DEPRESSION, OVERDOSE WITH BENZODIAZEPINE DRUGS, AND ENHANCEMENT OF MEMORY AND ALERTNESS | NEUROGEN CORPORATION | 2002-04-30 | — | — | US | disclosed |
| US-5023269-A | 3-aryloxy-3-substituted propanamines | ELI LILLY AND COMPANY (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0273658-B1 | 3-ARYLOXY-3-SUBSTITUTED PROPANAMINES | ELI LILLY AND COMPANY (US) | 1990-10-31 | — | — | EP | disclosed |
| US-4956388-A | ANTIDEPRESSANTS, ANTIANXIETY, TREATMENT OF OBESITY, ADDICTION TO SMOKING AND ALCOHOL | ELI LILLY AND COMPANY (US) | 1990-09-11 | — | — | US | disclosed |
| US-4902710-A | THIO-, SULFINYL-, OR SULFONYL-PROPANAMINES; ANTIDEPRESSANTS, ANXIOLYTIC AGENTS; NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| US-4053466-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, PLATELET AGGREGATION INHIBITORS | KOHJIN CO., LTD. (JA) | 1977-10-11 | — | — | US | disclosed |