SCHEMBL735087

SCHEMBL735087

CCCCCCc1cc[c]s1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.38
ADRA2A P08913 2/20 0.38
ADORA3 P0DMS8 2/20 0.38
TACR2 P21452 2/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
KCNH2 Q12809 2/20 0.38
HIF1A Q16665 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
SHBG P04278 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
HSPD1 P10809 1/20 0.38
ADRB3 P13945 1/20 0.38
HTR2C P28335 1/20 0.38
HSPE1 P61604 1/20 0.38
TST Q16762 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL987593 1.00 ESR1 (0.38) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL1286045 1.00 ESR1 (0.38) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL27868029 1.00 ESR1 (0.38) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL1285757 1.00 ESR1 (0.38) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL16892538 1.00 ESR1 (0.38) ESR1ADRA2AADORA3TACR2SLC6A2
Magnesium Chloride Anhydrous SCHEMBL28886869 0.93 HTR2A (0.38) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL3380 0.92
SCHEMBL16892561 0.86 SIGMAR1 (0.47) ALDH1A1LMNA
SCHEMBL16892539 0.86 SIGMAR1 (0.47) ALDH1A1LMNA
SCHEMBL16892552 0.86 ESR1 (0.36) ESR1TP53HSD17B10ACHEGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117615586-A Organic solar cell active layer based on liquid crystal molecules and application thereof 江西师范大学 2024-02-27 CN claimed
CN-117202682-A Composite tin-based perovskite film and preparation method and application thereof 极电光能有限公司 2023-12-08 CN claimed
CN-111154075-B Fluoroquinoxaline-thiophene copolymer and preparation method thereof 天津理工大学 2022-09-30 CN claimed
CN-114672003-A Conjugated polymer based on thiophene [3,4-c ] pyrrole-4, 6-diketone structure and preparation method and application thereof 天津理工大学 2022-06-28 CN claimed
CN-114213353-A Aryl-oxazole-oxazoline compound and preparation method and application thereof 贵州大学 2022-03-22 CN claimed
CN-109705137-B Doping-free hole transport material based on dithieno [3,2-b:2',3' -d ] pyrrole and synthetic method 南京理工大学 2021-05-04 CN claimed
CN-111154075-A Fluoroquinoxaline-thiophene copolymer and preparation method thereof 天津理工大学 2020-05-15 CN claimed
US-20110087034-A1 Organic Semiconductor Material SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2011-04-14 US claimed
EP-2248818-A1 ORGANIC SEMICONDUCTOR MATERIAL Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP claimed
EP-1165557-B1 ARYL AND HETEROARYL FUSED AMINOALKYL-IMIDAZOLE DERIVATIVES: SELECTIVE MODULATORS OF GABAa RECEPTORS NEUROGEN CORP (US) 2004-09-29 EP claimed
US-6627624-B1 Agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs of agonists, antagonists or inverse agonists for GABAa brain receptors, and are therefore useful in the diagnosis and treatment of anxiety, Down Syndrome, NEUROGEN CORPORATION 2003-09-30 US claimed
EP-3902023-B1 COMPOSITION CONTAINING ORGANIC SEMICONDUCTOR, SOLUTION FOR FORMING ORGANIC SEMICONDUCTOR LAYER, ORGANIC SEMICONDUCTOR LAYER, AND ORGANIC THIN FILM TRANSISTOR TOSOH CORP (JP) 2024-04-24 EP disclosed
CN-117615586-A Organic solar cell active layer based on liquid crystal molecules and application thereof 江西师范大学 2024-02-27 CN disclosed
CN-117304233-A Iridium metal complex, application thereof and organic electroluminescent device 清华大学 2023-12-29 CN disclosed
CN-117202682-A Composite tin-based perovskite film and preparation method and application thereof 极电光能有限公司 2023-12-08 CN disclosed
US-6627624-B1 Agonists, antagonists or inverse agonists for GABAa brain receptors or prodrugs of agonists, antagonists or inverse agonists for GABAa brain receptors, and are therefore useful in the diagnosis and treatment of anxiety, Down Syndrome, NEUROGEN CORPORATION 2003-09-30 US disclosed
US-6380210-B1 USEFUL IN DIAGNOSIS AND TREATMENT OF ANXIETY, DOWN SYNDROME, SLEEP, COGNITIVE AND SEIZURE DISORDERS, DEPRESSION, OVERDOSE WITH BENZODIAZEPINE DRUGS, AND ENHANCEMENT OF MEMORY AND ALERTNESS NEUROGEN CORPORATION 2002-04-30 US disclosed
EP-0035228-B1 TETRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND ANTI-ULCER COMPOSITION CONTAINING THE SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1985-01-02 EP disclosed
US-4372953-A Tetrazole derivatives, and anti-ulcer composition containing the same OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1983-02-08 US disclosed
EP-0035228-A1 Tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1981-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110087034-A1 Organic Semiconductor Material OR10J3, TST, OR51E2 ESR1 1107/4885ADRA2A 2494/4885ADORA3 2852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.