⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3480289 | 0.74 | — | — | |
| SCHEMBL442088 | 0.53 | — | — | |
| Ethylene Glycol SCHEMBL15227546 | 0.53 | TSHR (0.56) | — | |
| Methyl Alcohol SCHEMBL27283550 | 0.52 | — | — | |
| SCHEMBL1725771 | 0.52 | — | — | |
| SCHEMBL2965731 | 0.52 | — | — | |
| SCHEMBL126880 | 0.52 | — | — | |
| SCHEMBL28003084 | 0.52 | ALDH1A1 (0.33) | — | |
| SCHEMBL4366974 | 0.52 | — | — | |
| SCHEMBL290466 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414135-B1 | PHOSPHONYLATION OF ALKYLNUCLEOSIDE WITH BIS(TRIMETHYLSILYL)PHOSPHONITE IN BASE PRESENCE; CONCENTRATION; ADDING METHANOL SOLVENT; NUCLEASE RESISTANCE; HYBRIDIZATION | ISIS PHARMACEUTICALS, INC. | 2002-07-02 | — | — | US | claimed |
| US-11192907-B2 | Aminopeptidase A inhibitors and pharmaceutical compositions comprising the same | QUANTUM GENOMICS (FR) | 2021-12-07 | — | — | US | disclosed |
| US-20210309678-A1 | AMINOPEPTIDASE A INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Institut National de la Santé et de la Recherche Médicale (FR) | 2021-10-07 | — | — | US | disclosed |
| US-10131682-B2 | Hydrophilic linkers and their uses for conjugation of drugs to a cell binding molecules | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2018-11-20 | — | — | US | disclosed |
| US-20150250896-A1 | HYDROPHILIC LINKERS AND THEIR USES FOR CONJUGATION OF DRUGS TO A CELL BINDING MOLECULES | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2015-09-10 | — | — | US | disclosed |
| US-8119575-B2 | Gelation in presence of iron or aluminum salt of phosphonic acid or dialkylphosphinic acid | HALLIBURTON ENERGY SERVICES, INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-8097753-B2 | Mixtures composed or monocarboxy-functionalized dialkylphosphinic acids, their use and a process for their preparation | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-01-17 | — | — | US | disclosed |
| US-7862655-B2 | Subterranean cementing methods and compositions comprising oil suspensions of water soluble polymers | HALLIBURTON ENERGY SERVICES INC. (US) | 2011-01-04 | — | — | US | disclosed |
| US-7694739-B2 | Subterranean cementing methods and compositions comprising oil suspensions of water soluble polymers | HALLIBURTON ENERGY SERVICES, INC. (US) | 2010-04-13 | — | — | US | disclosed |
| US-7534745-B2 | Gelled invert emulsion compositions comprising polyvalent metal salts of an organophosphonic acid ester or an organophosphinic acid and methods of use and manufacture | HALLIBURTON ENERGY SERVICES, INC. (US) | 2009-05-19 | — | — | US | disclosed |
| US-6414135-B1 | PHOSPHONYLATION OF ALKYLNUCLEOSIDE WITH BIS(TRIMETHYLSILYL)PHOSPHONITE IN BASE PRESENCE; CONCENTRATION; ADDING METHANOL SOLVENT; NUCLEASE RESISTANCE; HYBRIDIZATION | ISIS PHARMACEUTICALS, INC. | 2002-07-02 | — | — | US | disclosed |
| EP-0923585-B1 | PHOSPHINATE BASED INHIBITORS OF MATRIX METALLOPROTEASES | PFIZER (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001036003-A2 | SELECTIVE CELLULAR TARGETING: MULTIFUNCTIONAL DELIVERY VEHICLES | DRUG INNOVATION & DESIGN, INC. (US) | 2001-05-25 | — | — | WO | disclosed |
| US-6147061-A | ANTIARTHRITIC AGENTS; ANTICANCER AGENTS; ORAL DISEASES | PFIZER INC. (US) | 2000-11-14 | — | — | US | disclosed |
| EP-0767794-B1 | PHOSPHINIC ACID DERIVATIVES | SCHERING CORP (US) | 2000-02-02 | — | — | EP | disclosed |
| CN-1225639-A | Phosphinate-Based Matrix Metalloproteinase Inhibitors | PFIZER (US) | 1999-08-11 | — | — | CN | disclosed |
| EP-0767794-A1 | PHOSPHINIC ACID DERIVATIVES | SCHERING CORPORATION (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000732-A9 | PHOSPHINIC ACID DERIVATIVES | — | 1996-02-22 | — | — | WO | disclosed |
| WO-1996000732-A1 | PHOSPHINIC ACID DERIVATIVES | SCHERING CORPORATION (US) | 1996-01-11 | — | — | WO | disclosed |
| US-5476847-A | Treating cardiovascular, gastrointestinal, urogenital disorders | SCHERING CORPORATION (US) | 1995-12-19 | — | — | US | disclosed |