Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.66 |
| ▸ | HTR1A | P08908 | 5/20 | 0.66 |
| ▸ | HTR2C | P28335 | 4/20 | 0.66 |
| ▸ | HTR2B | P41595 | 3/20 | 0.66 |
| ▸ | HTR6 | P50406 | 4/20 | 0.62 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.58 |
| ▸ | HTR1D | P28221 | 2/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | HRH1 | P35367 | 2/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | HTR1E | P28566 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378673 | 0.86 | HTR2A (0.70) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| SCHEMBL3378323 | 0.86 | HTR2A (0.70) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| Hydrochloric Acid SCHEMBL9393120 | 0.85 | HTR2A (0.68) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| SCHEMBL4985934 | 0.80 | HTR2A (0.77) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| SCHEMBL26688728 | 0.80 | HTR2A (0.65) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| N,N-Dimethyltryptamine SCHEMBL29350959 | 0.79 | HTR2A (1.00) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| N,N-Dimethyltryptamine SCHEMBL335710 | 0.79 | HTR2A (1.00) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| SCHEMBL6933897 | 0.79 | HTR2A (0.70) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| SCHEMBL30896267 | 0.79 | HTR2A (0.81) | HTR2AHTR1AHTR2CHTR2BHTR6 | |
| N,N-Dimethyltryptamine SCHEMBL27221709 | 0.79 | HTR2A (1.00) | HTR2AHTR1AHTR2CHTR2BHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | claimed |
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | disclosed |