SCHEMBL3380293

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29740965	0.89	BTK (0.59)	TRPA1ARCDK5CLK4DYRK1B
	SCHEMBL3378316	0.89	BTK (0.59)	TRPA1ARCDK5CLK4DYRK1B
	SCHEMBL11890140	0.84	TRPA1 (0.60)	TRPA1ARTRPM8TGFBR1CDK5
	SCHEMBL27810091	0.83	TRPA1 (0.66)	TRPA1ARTRPM8TGFBR1CDK5
	SCHEMBL17593702	0.81	PARP1 (0.47)	TRPA1ARTGFBR1CDK5CLK4
	SCHEMBL30627398	0.80	TGFBR1 (0.50)	TRPA1ARTGFBR1CDK5CLK4
	SCHEMBL7572389	0.80	TGFBR1 (0.50)	TRPA1ARTGFBR1CDK5CLK4
	SCHEMBL20509685	0.80	AR (0.53)	TRPA1ARTGFBR1CDK5CLK4
	SCHEMBL17593699	0.80	CCNC (0.50)	TRPA1ARCDK5CLK4DYRK1B
	SCHEMBL27663175	0.78	TRPA1 (0.68)	TRPA1TRPM8TGFBR1CDK5CLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.