Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15042018 | 0.86 | POLB (0.52) | ALDH1A1POLBKDM4EHPGDMEN1 | |
| SCHEMBL8399946 | 0.81 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2POLBKDM4ETSHR | |
| SCHEMBL15042019 | 0.76 | POLB (0.66) | ALDH1A1POLBKDM4EHPGDMEN1 | |
| SCHEMBL7460811 | 0.75 | ALDH1A1 (0.54) | ALDH1A1HPGDKMT2ATSHR | |
| SCHEMBL25075268 | 0.74 | POLB (0.41) | POLBKMT2A | |
| SCHEMBL15042180 | 0.74 | POLB (0.48) | ALDH1A1SMN1; SMN2POLBHPGDMEN1 | |
| SCHEMBL15042126 | 0.72 | POLB (0.46) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL15042027 | 0.71 | BRD4 (0.55) | ALDH1A1SMN1; SMN2POLBHPGDMEN1 | |
| SCHEMBL16931294 | 0.71 | NPSR1 (0.36) | ALDH1A1LIPEMEN1KMT2AMAPT | |
| SCHEMBL16931293 | 0.71 | NPSR1 (0.36) | ALDH1A1LIPEMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976815-B1 | Lubricating composition with improved bearing corrosion protection | LUBRIZOL CORP (US) | 2010-12-01 | — | — | EP | disclosed |
| EP-0743353-B2 | Additive combinations for lubricants and functional fluids | LUBRIZOL CORP (US) | 2008-08-06 | — | — | EP | disclosed |
| EP-0972819-B1 | Lubricating compositions | LUBRIZOL CORP (US) | 2008-04-09 | — | — | EP | disclosed |
| EP-0976814-B1 | Lubricating compositions with reduced bearing corrosion | LUBRIZOL CORP (US) | 2004-03-17 | — | — | EP | disclosed |
| EP-0743353-B1 | Additive combinations for lubricants and functional fluids | LUBRIZOL CORP (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-0787791-B1 | Functional fluid compositions having improved frictional and anti-oxidation properties | LUBRIZOL CORP (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-0747464-B1 | A composition for providing anti-shudder friction durability performance for automatic transmissions | LUBRIZOL CORP (US) | 2001-07-25 | — | — | EP | disclosed |
| US-6207624-B1 | Engine oil having dispersant and aldehyde/epoxide for improved seal performance, sludge and deposit performance | THE LUBRIZOL CORPORATION | 2001-03-27 | — | — | US | disclosed |
| EP-0976814-A1 | Lubricating compositions with reduced bearing corrosion | The Lubrizol Corporation (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976815-A2 | Lubricating composition with improved bearing corrosion protection | The Lubrizol Corporation (US) | 2000-02-02 | — | — | EP | disclosed |
| US-4582543-A | WITH AN OVERBASED COMPOUND-CORROSION INHIBITING COATING | THE LUBRIZOL CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0172906-A1 | PROCESS FOR MAKING SUBSTITUTED CARBOXYLIC ACIDS AND DERIVATIVES THEREOF. | LUBRIZOL CORP (US) | 1986-03-05 | — | — | EP | disclosed |
| WO-1986000081-A1 | ALKENYL-SUBSTITUTED CARBOXYLIC ACYLATING AGENT/HYDROXY TERMINATED POLYOXYALKYLENE REACTION PRODUCTS AND AQUEOUS SYSTEMS CONTAINING SAME | THE LUBRIZOL CORPORATION (US) | 1986-01-03 | — | — | WO | disclosed |
| WO-1985003504-A2 | PROCESS FOR MAKING SUBSTITUTED CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | THE LUBRIZOL CORPORATION (US) | 1985-08-15 | — | — | WO | disclosed |
| US-4468339-A | AND SOLUBILIZER WHICH IS REACTION OF CARBOXYLIC ACID ACYLATING AGENT WITH HYDROCARBON SUBSTITMENT AND HYDROXYAMINE | THE LUBRIZOL CORPORATION (US) | 1984-08-28 | — | — | US | disclosed |
| US-4448703-A | Carboxylic solubilizer/surfactant combinations and aqueous compositions containing same | THE LUBRIZOL CORPORATION (US) | 1984-05-15 | — | — | US | disclosed |
| US-4447348-A | Carboxylic solubilizer/surfactant combinations and aqueous compositions containing same | THE LUBRIZOL CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |
| EP-0084966-A2 | Aqueous compositions containing overbased materials | The Lubrizol Corporation (US) | 1983-08-03 | — | — | EP | disclosed |
| US-4368133-A | Aqueous systems containing nitrogen-containing, phosphorous-free carboxylic solubilizer/surfactant additives | THE LUBRIZOL CORPORATION (US) | 1983-01-11 | — | — | US | disclosed |
| US-4234435-A | Novel carboxylic acid acylating agents, derivatives thereof, concentrate and lubricant compositions containing the same, and processes for their preparation | THE LUBRIZOL CORPORATION (US) | 1980-11-18 | — | — | US | disclosed |