Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20488351 | 0.87 | KMT2A (0.55) | ALDH1A1LMNAKMT2A | |
| SCHEMBL31581789 | 0.84 | ALDH1A1 (0.54) | ALDH1A1HPGDTSHRMAPK1L3MBTL1 | |
| SCHEMBL7464776 | 0.83 | SMN1; SMN2 (0.56) | ALDH1A1HPGDTSHRL3MBTL1LMNA | |
| SCHEMBL8535575 | 0.78 | KMT2A (0.55) | ALDH1A1KMT2A | |
| SCHEMBL14022760 | 0.78 | L3MBTL1 (0.74) | ALDH1A1L3MBTL1ATMTDP1 | |
| SCHEMBL5166634 | 0.78 | KMT2A (0.55) | ALDH1A1KMT2A | |
| SCHEMBL8263564 | 0.78 | L3MBTL1 (0.74) | ALDH1A1L3MBTL1ATMTDP1 | |
| SCHEMBL1545229 | 0.78 | L3MBTL1 (0.74) | ALDH1A1L3MBTL1ATMTDP1 | |
| SCHEMBL8399946 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TSHRMAPK1LMNA | |
| SCHEMBL1872029 | 0.77 | L3MBTL1 (0.65) | ALDH1A1L3MBTL1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1180513-A1 | CYCLIC AMIDE COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-02-20 | — | — | EP | disclosed |