SCHEMBL3380503

SCHEMBL3380503

O=C(O)c1ccc2c(c1)C(=O)[N]C2=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 3/20 0.55
PTPRC P08575 2/20 0.53
POLB P06746 4/20 0.50
KMT2A Q03164 3/20 0.50
ALDH1A1 P00352 2/20 0.45
HPGD P15428 3/20 0.45
MEN1 O00255 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
MAPT P10636 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
CDC25A P30304 1/20 0.45
CDC25B P30305 1/20 0.45
CTDSP1 Q9GZU7 1/20 0.45
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KDM4E B2RXH2 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2976406 0.88 TTR (0.55) TTRPTPRCPOLBKMT2AALDH1A1
SCHEMBL8432111 0.77 TTR (0.49) TTRPTPRCPOLBKMT2AALDH1A1
SCHEMBL69805 0.77 PTPRC (0.72) TTRPTPRCPOLBKMT2AHPGD
SCHEMBL68062 0.77 PTPRC (0.72) TTRPTPRCPOLBKMT2AHPGD
SCHEMBL600296 0.76 TTR (0.80) TTRPTPRCPOLBKMT2AALDH1A1
SCHEMBL31686219 0.76 PTPRC (0.84) TTRPTPRCPOLBKMT2AALDH1A1
SCHEMBL31436145 0.76 TTR (0.88) TTRPTPRCPOLBKMT2AALDH1A1
SCHEMBL598301 0.76 TTR (0.88) TTRPTPRCPOLBKMT2AALDH1A1
SCHEMBL71021 0.76 TTR (0.88) TTRPTPRCPOLBKMT2AALDH1A1
SCHEMBL31086890 0.76 TTR (0.80) TTRPTPRCPOLBKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0412101-B1 NOVEL METHINE COMPOUNDS, POLYMERS CONTAINING THEM AND FORMED ARTICLES THEREFROM EASTMAN KODAK CO (US) 1993-10-27 EP claimed
US-5086161-A Ultraviolet radiation screening food packaging EASTMAN KODAK COMPANY (US) 1992-02-04 US claimed
EP-0412101-A1 NOVEL METHINE COMPOUNDS, POLYMERS CONTAINING THEM AND FORMED ARTICLES THEREFROM. EASTMAN KODAK CO (US) 1991-02-13 EP claimed
EP-0235198-B1 COLORED UNSATURATED POLYESTER MATERIAL CONTAINING COPOLYMERIZED METHINE DYES, AND PRODUCTS THEREFROM EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-12-05 EP claimed
EP-0215054-B1 CONDENSATION POLYMERS AND PRODUCTS THEREFROM EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-01-03 EP claimed
WO-1989010349-A2 NOVEL METHINE COMPOUNDS, POLYMERS CONTAINING THEM AND FORMED ARTICLES THEREFROM EASTMAN KODAK COMPANY (US) 1989-11-02 WO claimed
US-4804719-A PRINTING INKS; COATINGS; HEAT AND COLD RESISTANCE EASTMAN KODAK COMPANY (US) 1989-02-14 US claimed
EP-0235198-A1 COLORED UNSATURATED POLYESTER MATERIAL CONTAINING COPOLYMERIZED METHINE DYES, AND PRODUCTS THEREFROM. EASTMAN KODAK CO (US) 1987-09-09 EP claimed
EP-0215054-A1 CONDENSATION POLYMERS AND PRODUCTS THEREFROM. EASTMAN KODAK CO (US) 1987-03-25 EP claimed
WO-1987001121-A1 COLORED UNSATURATED POLYESTER MATERIAL CONTAINING COPOLYMERIZED METHINE DYES, AND PRODUCTS THEREFROM EASTMAN KODAK COMPANY (US) 1987-02-26 WO claimed
US-4617373-A POLYESTERS CONDENSED WITH METHINE GROUP CONTAINING COMPOUNDS; MOLDING MATERIALS EASTMAN KODAK COMPANY (US) 1986-10-14 US claimed
WO-1986004904-A1 CONDENSATION POLYMERS AND PRODUCTS THEREFROM EASTMAN KODAK COMPANY (US) 1986-08-28 WO claimed
US-4052373-A O-AMINOESTER FUJI PHOTO FILM CO., LTD. (JA) 1977-10-04 US claimed
US-8470844-B2 Imidazoacridinone derivative compounds and methods for their use TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2013-06-25 US disclosed
US-20100137351-A1 Imidazoacridinone derivative compounds and methods for their use TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) 2010-06-03 US disclosed
WO-2006002022-A2 COMPOSITIONS AND METHODS USEFUL FOR THE TREATMENT OF HYPERGLYCEMIA IMMUSOL INCORPORATED (US) 2006-01-05 WO disclosed
WO-1987001121-A1 COLORED UNSATURATED POLYESTER MATERIAL CONTAINING COPOLYMERIZED METHINE DYES, AND PRODUCTS THEREFROM EASTMAN KODAK COMPANY (US) 1987-02-26 WO disclosed
US-4617373-A POLYESTERS CONDENSED WITH METHINE GROUP CONTAINING COMPOUNDS; MOLDING MATERIALS EASTMAN KODAK COMPANY (US) 1986-10-14 US disclosed
WO-1986004904-A1 CONDENSATION POLYMERS AND PRODUCTS THEREFROM EASTMAN KODAK COMPANY (US) 1986-08-28 WO disclosed
US-4052373-A O-AMINOESTER FUJI PHOTO FILM CO., LTD. (JA) 1977-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137351-A1 Imidazoacridinone derivative compounds and methods for their use IDH3A, IDH3B, ABL1 TTR 2579/4885PTPRC 3103/4885POLB 925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.