Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.49 |
| ▸ | PTPRC | P08575 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380503 | 0.77 | TTR (0.55) | TTRPTPRCPOLBKMT2AALDH1A1 | |
| SCHEMBL2976406 | 0.77 | TTR (0.55) | TTRPTPRCPOLBKMT2AALDH1A1 | |
| SCHEMBL8432114 | 0.75 | F2 (0.36) | KMT2AALDH1A1HPGDMEN1TDP1 | |
| SCHEMBL13196215 | 0.74 | CDC25B (0.59) | TTRPTPRCPOLBKMT2ACSNK2A2 | |
| SCHEMBL69805 | 0.71 | PTPRC (0.72) | TTRPTPRCPOLBKMT2ACA1 | |
| SCHEMBL68062 | 0.71 | PTPRC (0.72) | TTRPTPRCPOLBKMT2ACA1 | |
| Hydrochloric Acid SCHEMBL2097036 | 0.70 | S100A4 (0.47) | PTPRCKMT2AALDH1A1CA1CA2 | |
| SCHEMBL15900800 | 0.70 | KDM4E (0.55) | TTRPTPRCPOLBKMT2ACSNK2A2 | |
| SCHEMBL71021 | 0.70 | TTR (0.88) | TTRPTPRCPOLBKMT2ACSNK2A2 | |
| SCHEMBL598301 | 0.70 | TTR (0.88) | TTRPTPRCPOLBKMT2ACSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847749-B1 | Use of diiminoisoindoline or 3-aminoisoindolone derivatives for the dyeing of keratinic fibers and compositions containing them | OREAL (FR) | 1999-12-01 | — | — | EP | claimed |