Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.66 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354308 | 1.00 | SIGMAR1 (0.66) | SIGMAR1TMEM97LMNADHODHALDH1A1 | |
| SCHEMBL3354305 | 1.00 | SIGMAR1 (0.66) | SIGMAR1TMEM97LMNADHODHALDH1A1 | |
| SCHEMBL959673 | 0.90 | TMEM97 (0.55) | SIGMAR1TMEM97DHODHADAM10ERBB2 | |
| SCHEMBL3378446 | 0.83 | SIGMAR1 (0.58) | SIGMAR1TMEM97DHODHKMT2A | |
| SCHEMBL3379565 | 0.83 | SIGMAR1 (0.58) | SIGMAR1TMEM97DHODHKMT2A | |
| SCHEMBL955851 | 0.83 | SIGMAR1 (0.58) | SIGMAR1TMEM97DHODHKMT2A | |
| Oxalic Acid SCHEMBL955643 | 0.82 | SIGMAR1 (0.90) | SIGMAR1TMEM97DHODHALDH1A1HSP90AA1 | |
| SCHEMBL3383254 | 0.80 | SIGMAR1 (1.00) | SIGMAR1TMEM97DHODHALDH1A1HSP90AA1 | |
| SCHEMBL3381500 | 0.80 | SIGMAR1 (1.00) | SIGMAR1TMEM97DHODHALDH1A1HSP90AA1 | |
| SCHEMBL954332 | 0.80 | SIGMAR1 (1.00) | SIGMAR1TMEM97DHODHALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010066829-A1 | PROCESS FOR OBTAINING ENANTIOMERICALLY ENRICHED PYRAZOLE DERIVATIVES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2010-06-17 | — | — | WO | disclosed |
| WO-2010066829-A1 | PROCESS FOR OBTAINING ENANTIOMERICALLY ENRICHED PYRAZOLE DERIVATIVES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2010-06-17 | — | — | WO | disclosed |
| EP-2196458-A1 | Process for obtaining enantiomerically enriched pyrazole derivatives | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2010-06-16 | — | — | EP | disclosed |
| EP-2196458-A1 | Process for obtaining enantiomerically enriched pyrazole derivatives | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2010-06-16 | — | — | EP | disclosed |