SCHEMBL338117

SCHEMBL338117

Sc1ccc(Cc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.67
LTA4H P09960 4/20 0.50
IDH1 O75874 1/20 0.48
PLA2G10 O15496 1/20 0.46
PLA2G2A P14555 1/20 0.46
LMNA P02545 1/20 0.46
IDO1 P14902 1/20 0.46
SLC22A2 O15244 1/20 0.45
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
BCL2 P10415 1/20 0.41
BCL2L1 Q07817 1/20 0.41
CYP2C9 P11712 1/20 0.41
HNF4A P41235 1/20 0.41
TP53 P04637 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28040186 0.97 CALM1 (0.63) CALM1LTA4HIDH1PLA2G10PLA2G2A
SCHEMBL28040181 0.97 CALM1 (0.63) CALM1LTA4HIDH1PLA2G10PLA2G2A
SCHEMBL17416126 0.97 CALM1 (0.63) CALM1LTA4HIDH1PLA2G10PLA2G2A
Diphenylmethane SCHEMBL6200261 0.92 CALM1 (0.71) CALM1LTA4HIDH1PLA2G10PLA2G2A
SCHEMBL63938 0.88 ALDH1A1 (0.47) CALM1LTA4HIDH1PLA2G10PLA2G2A
Hydrochloric Acid SCHEMBL9051020 0.85 ALDH1A1 (0.45) CALM1LTA4HIDH1PLA2G10PLA2G2A
SCHEMBL972712 0.85 CALM1 (0.92) CALM1LTA4HIDH1PLA2G10PLA2G2A
SCHEMBL8094422 0.85 CALM1 (0.92) CALM1LTA4HIDH1PLA2G10PLA2G2A
SCHEMBL9456420 0.83 MAOB (0.56) IDO1LOXL2
Hydrochloric Acid SCHEMBL27978245 0.82 CALM1 (0.86) CALM1LTA4HIDH1PLA2G10PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106957650-A A kind of preparation method for modifying quantum dot and modification quantum dot film 深圳市华星光电技术有限公司 2017-07-18 CN claimed
US-4299843-A Stabilized cyandhydrin ester SHELL OIL COMPANY (US) 1981-11-10 US claimed
CN-120065622-A Photosensitive resin composition and method for producing microlens 东京应化工业株式会社 2025-05-30 CN disclosed
CN-119620544-A Photosensitive resin composition, dry film, photosensitive dry film, resist film, molded substrate with mold, and method for producing plated molded article 东京应化工业株式会社 2025-03-14 CN disclosed
CN-110317174-B Hydrogen barrier agent, composition for forming hydrogen barrier film, method for producing hydrogen barrier film, and electronic device 东京应化工业株式会社 2024-10-22 CN disclosed
CN-118829948-A Method for manufacturing plating shaped article 东京应化工业株式会社 2024-10-22 CN disclosed
CN-118742854-A Chemically amplified positive photosensitive composition, method for producing molded substrate with mold, and method for producing plated molded article 东京应化工业株式会社 2024-10-01 CN disclosed
WO-2024125600-A1 HETEROCYCLIC COMPOUNDS ACTING AS KRAS INHIBITORS, PREPARATION THEREFOR AND THERAPEUTIC USE THEREOF 上海科州药物研发有限公司 2024-06-20 WO disclosed
WO-2024061366-A1 SMALL MOLECULE COMPOUND HAVING PHOSPHORYLATED ARYL STRUCTURE, AND USE THEREOF 杭州天玑济世生物科技有限公司 2024-03-28 WO disclosed
WO-2024046370-A1 HETEROCYCLIC COMPOUNDS AS KRAS INHIBITORS, AND PREPARATION AND THERAPEUTIC USE THEREOF 上海科州药物研发有限公司 2024-03-07 WO disclosed
CN-110647010-B Resin composition, dry film, method for producing dry film, resist film, substrate, and method for producing plating molded article 东京应化工业株式会社 2024-02-09 CN disclosed
EP-0786992-A2 LTA 4? HYDROLASE INHIBITOR PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE G.D. SEARLE & CO. (US) 1997-08-06 EP disclosed
WO-1997020815-A1 COMPOUNDS ASTRA PHARMACEUTICALS LTD. (GB) 1997-06-12 WO disclosed
US-5585492-A USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES WHICH ARE MEDIATED BY LTB4 PRODUCTION, SUCH AS PSORIASIS, ULCERATIVE COLITIS, IRRITABLE BOWEL DISEASE AND ASTHMA G. D. SEARLE & CO. (US) 1996-12-17 US disclosed
WO-1996022770-A1 ANTI-INFLAMMATORY COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 1996-08-01 WO disclosed
WO-1996011192-A1 LTA4 HYDROLASE INHIBITORS G.D. SEARLE & CO. (US) 1996-04-18 WO disclosed
WO-1996010999-A2 LTA4 HYDROLASE INHIBITOR PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE G.D. SEARLE & CO. (US) 1996-04-18 WO disclosed
US-5496855-A Anti-inflammatory compounds SMITHKLINE BEECHAM CORP. (US) 1996-03-05 US disclosed
US-4670592-A BACTERICIDES, FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-06-02 US disclosed
US-4229478-A Naphthaquinone anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1980-10-21 US disclosed