Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.66 |
| ▸ | CA1 | P00915 | 5/20 | 0.66 |
| ▸ | CA2 | P00918 | 5/20 | 0.66 |
| ▸ | CA7 | P43166 | 5/20 | 0.66 |
| ▸ | CA9 | Q16790 | 5/20 | 0.66 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.66 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812160 | 0.83 | CA12 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17594423 | 0.83 | LMNA (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28289517 | 0.83 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13193177 | 0.83 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30863575 | 0.82 | CA1 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL399625 | 0.82 | CA1 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4694878 | 0.82 | HSD17B2 (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13812237 | 0.82 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| Water SCHEMBL16678551 | 0.82 | CA12 (0.96) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6990343 | 0.81 | CA12 (0.53) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171883-A1 | ANTIVIRAL WIPER | FUJIFILM CORPORATION (JP) | 2021-06-10 | — | — | US | disclosed |
| CN-106674042-A | Method for preparing 3-cyan-4-hydroxy ethyl benzoate | 苏州山青竹生物医药有限公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-106674042-A | Method for preparing 3-cyan-4-hydroxy ethyl benzoate | 苏州山青竹生物医药有限公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-106674054-A | Method for preparing 3-cyan-4-isopropoxy ethyl benzoate | 苏州山青竹生物医药有限公司 | 2017-05-17 | — | — | CN | disclosed |
| US-8097652-B2 | AMPA receptor potentiators | ELI LILLY AND COMPANY (US) | 2012-01-17 | — | — | US | disclosed |
| US-20100010090-A1 | AMPA RECEPTOR POTENTIATORS | ELI LILLY AND COMPANY | 2010-01-14 | — | — | US | disclosed |
| EP-2102153-A1 | AMPA RECEPTOR POTENTIATORS | Eli Lilly & Company (US) | 2009-09-23 | — | — | EP | disclosed |
| EP-1893597-B1 | AMPA RECEPTOR POTENTIATORS | LILLY CO ELI (US) | 2008-11-12 | — | — | EP | disclosed |
| EP-1452528-B1 | XANTHINE OXIDASE INHIBITORS | NIPPON CHEMIPHAR CO (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-7393868-B2 | AMPA receptor potentiators | ELI LILLY AND COMPANY (US) | 2008-07-01 | — | — | US | disclosed |
| WO-2008073789-A1 | AMPA RECEPTOR POTENTIATORS | ELI LILLY AND COMPANY (US) | 2008-06-19 | — | — | WO | disclosed |
| EP-1893597-A2 | AMPA RECEPTOR POTENTIATORS | ELI LILLY AND COMPANY (US) | 2008-03-05 | — | — | EP | disclosed |
| US-20070265283-A1 | Xanthine Oxidase Inhibitor | NIPPON CHEMIPHAR CO., LTD. | 2007-11-15 | — | — | US | disclosed |
| US-7253154-B2 | Substituted thiazolopyrimidines as xanthine oxidase inhibitors | NIPPON CHEMIPHAR CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-20070142441-A1 | AMPA receptor potentiators | ELI LILLY AND COMPANY | 2007-06-21 | — | — | US | disclosed |
| WO-2006132811-A2 | AMPA RECEPTOR POTENTIATORS | ELI LILLY AND COMPANY (US) | 2006-12-14 | — | — | WO | disclosed |
| US-20050090472-A1 | Xanthine oxidase inhibitors | NIPPON CHEMIPHAR CO., LTD. (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1452528-A1 | XANTHINE OXIDASE INHIBITORS | NIPPON CHEMIPHAR CO., LTD. (JP) | 2004-09-01 | — | — | EP | disclosed |
| US-4151297-A | Bicyclo [3.1.0] hexyl-substituted ethylamino carbonyl phenoxy cardiovascular agents | SYNTEX (U.S.A.) INC. (US) | 1979-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142441-A1 | AMPA receptor potentiators | GABRE, GRIN1, GRIK2 | CA12 2225/4885CA1 522/4885CA2 625/4885 |
| US-20210171883-A1 | ANTIVIRAL WIPER | CGAS, PRKX, PDE4C | CA12 2396/4885CA1 2414/4885CA2 1789/4885 |
| US-20100010090-A1 | AMPA RECEPTOR POTENTIATORS | GRIN1, GRIK2, GRIK1 | CA12 2984/4885CA1 856/4885CA2 1049/4885 |
| US-20050090472-A1 | Xanthine oxidase inhibitors | XDH, CBR1, NOX1 | CA12 1249/4885CA1 968/4885CA2 900/4885 |
| US-20070265283-A1 | Xanthine Oxidase Inhibitor | XDH, CBR1, NOX1 | CA12 1276/4885CA1 1007/4885CA2 951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.