Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381888 | 1.00 | TDP1 (0.40) | TDP1SMN1; SMN2SLC22A6TSHRFOLH1 | |
| SCHEMBL3379978 | 0.82 | ALOX15 (0.31) | KMT2A | |
| SCHEMBL3379982 | 0.82 | ALOX15 (0.31) | KMT2A | |
| SCHEMBL3381808 | 0.80 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6TSHRFOLH1 | |
| SCHEMBL3381805 | 0.80 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6TSHRFOLH1 | |
| SCHEMBL3381192 | 0.80 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6TSHRFOLH1 | |
| SCHEMBL3381196 | 0.80 | TDP1 (0.43) | TDP1SMN1; SMN2SLC22A6TSHRFOLH1 | |
| SCHEMBL3380281 | 0.78 | — | — | |
| SCHEMBL3380275 | 0.78 | — | — | |
| SCHEMBL3377867 | 0.77 | TET2 (0.43) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | disclosed |