Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381913 | 1.00 | OTC (0.35) | OTCALOX15MEN1KMT2ACYP1A2 | |
| SCHEMBL3382059 | 0.87 | ALOX15 (0.36) | OTCALOX15MEN1KMT2ACYP1A2 | |
| SCHEMBL3382062 | 0.87 | ALOX15 (0.36) | OTCALOX15MEN1KMT2ACYP1A2 | |
| SCHEMBL3377213 | 0.87 | ALOX15 (0.36) | OTCALOX15MEN1KMT2ACYP1A2 | |
| SCHEMBL3377211 | 0.87 | ALOX15 (0.36) | OTCALOX15MEN1KMT2ACYP1A2 | |
| SCHEMBL28986669 | 0.82 | ALOX15 (0.37) | OTCALOX15MEN1KMT2ACYP1A2 | |
| SCHEMBL196827 | 0.81 | NOS2 (0.38) | OTCALOX15MEN1KMT2ACYP1A2 | |
| SCHEMBL160690 | 0.81 | NOS2 (0.38) | OTCALOX15MEN1KMT2ACYP1A2 | |
| SCHEMBL288819 | 0.81 | NOS2 (0.38) | OTCALOX15MEN1KMT2ACYP1A2 | |
| SCHEMBL2673036 | 0.81 | ALOX15 (0.36) | OTCALOX15MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | claimed |
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | disclosed |