Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 10/20 | 0.42 |
| ▸ | MEN1 | O00255 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3232335 | 0.84 | HTR1D (0.61) | HTR1DHTR6MTNR1AMTNR1BMAPT | |
| SCHEMBL3262319 | 0.83 | HTR1D (0.46) | HTR1DHTR6MTNR1AMTNR1BMAPT | |
| SCHEMBL3382767 | 0.75 | KDM4E (0.56) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL31440934 | 0.75 | HTR2A (0.59) | MTNR1AMTNR1BHTR2AHTTALDH1A1 | |
| SCHEMBL25748613 | 0.75 | HTR2A (0.59) | MTNR1AMTNR1BHTR2AHTTALDH1A1 | |
| SCHEMBL3264690 | 0.74 | AKR1C2 (0.47) | HTR1DHTR6MTNR1AMTNR1BMAPT | |
| SCHEMBL13492871 | 0.74 | MTNR1A (0.60) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL13492873 | 0.73 | ATM (0.63) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL16711790 | 0.72 | KDM4E (0.45) | MTNR1AMTNR1BPOLBALDH1A1KDM4E | |
| SCHEMBL18509381 | 0.70 | HTR1D (0.61) | HTR1DHTR6MTNR1AMTNR1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | disclosed |