Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 13/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263047 | 0.83 | MAPT (0.39) | KDM4EMEN1GAAMAPTKMT2A | |
| SCHEMBL3261013 | 0.81 | SIRT1 (0.39) | AKR1C2KDM4EMEN1GAAMAPT | |
| SCHEMBL3379855 | 0.81 | MAP2 (0.47) | KDM4EMEN1GAAMAPTKMT2A | |
| SCHEMBL3232335 | 0.80 | HTR1D (0.61) | AKR1C2HTR1DHTR6TAAR1MTNR1A | |
| SCHEMBL3382968 | 0.78 | ICMT (0.38) | KDM4EMEN1GAAMAPTKMT2A | |
| SCHEMBL4245648 | 0.77 | AKR1C2 (0.78) | AKR1C2HTR1DHTR6MTNR1AMTNR1B | |
| SCHEMBL3262319 | 0.76 | HTR1D (0.46) | AKR1C2HTR1DHTR6TAAR1MTNR1A | |
| SCHEMBL3636076 | 0.76 | KDM4E (0.55) | KDM4EMEN1GAAMAPTKMT2A | |
| SCHEMBL3382133 | 0.74 | HTR1D (0.44) | HTR1DHTR6TAAR1MTNR1AMTNR1B | |
| SCHEMBL7956382 | 0.74 | AKR1C2 (0.61) | AKR1C2HTR1DHTR6PLA2G2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012396-A1 | 5,6 SUBSTITUTED BENZAMIDE DERIVATIVES AS MODULATORS OF THE EP<SB>2 </SB>RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-04 | — | — | WO | disclosed |