Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3382202 | 1.00 | GSR (0.52) | GSRRNPEPCPB2FOLH1CYP2D6 | |
| SCHEMBL3380824 | 0.94 | CPB2 (0.45) | GSRRNPEPCPB2FOLH1CYP2D6 | |
| SCHEMBL3380820 | 0.94 | CPB2 (0.45) | GSRRNPEPCPB2FOLH1CYP2D6 | |
| SCHEMBL3380827 | 0.94 | CPB2 (0.45) | GSRRNPEPCPB2FOLH1CYP2D6 | |
| SCHEMBL3379275 | 0.86 | GSR (0.50) | GSRRNPEPCPB2FOLH1CYP2D6 | |
| SCHEMBL3379272 | 0.86 | GSR (0.50) | GSRRNPEPCPB2FOLH1CYP2D6 | |
| SCHEMBL18531957 | 0.86 | GSR (0.50) | GSRRNPEPCPB2FOLH1CYP2D6 | |
| SCHEMBL11711858 | 0.84 | GPR84 (0.33) | GSRBLMLMNA | |
| SCHEMBL3379369 | 0.84 | GSR (0.48) | GSRRNPEPCPB2FOLH1CYP2D6 | |
| SCHEMBL3379367 | 0.84 | GSR (0.48) | GSRRNPEPCPB2FOLH1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | disclosed |
| US-4015008-A | N,N-dichloro substituted aminocarboxylic acids as microbiocides | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |
| US-3950536-A | N,N-Dichloro substituted aminocarboxylic acids as bactericides and fungicides | BARER SOL JOSEPH | 1976-04-13 | — | — | US | disclosed |