Perflubron

Perflubron

SCHEMBL33826

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Br

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 1.00
THRB P10828 1/20 0.36
CA2 P00918 2/20 0.33
CA1 P00915 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31720936 1.00 LMNA (1.00) LMNATHRBCA2CA1MMP1
SCHEMBL2722025 1.00 LMNA (1.00) LMNATHRBCA2CA1MMP1
Perflubron SCHEMBL13724347 1.00 LMNA (1.00) LMNATHRBCA2CA1MMP1
Perflubrodec SCHEMBL364093 1.00 LMNA (1.00) LMNATHRBCA2CA1MMP1
SCHEMBL7029311 1.00 LMNA (1.00) LMNATHRBCA2CA1MMP1
SCHEMBL7055048 1.00 LMNA (1.00) LMNATHRBCA2CA1MMP1
Perflubron SCHEMBL8040555 1.00 LMNA (1.00) LMNATHRBCA2CA1MMP1
SCHEMBL4511229 1.00 LMNA (1.00) LMNATHRBCA2CA1MMP1
SCHEMBL249369 1.00 LMNA (1.00) LMNATHRBCA2CA1MMP1
SCHEMBL248644 1.00 LMNA (1.00) LMNATHRBCA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15502 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075746-A Microsphere composition, preparation method thereof and application thereof in preparation of contrast agent and medicine 2026-05-26 CN claimed
WO-2026106498-A1 PERFUSION FLUID, METHODS OF PRODUCING PERFUSION FLUID, AND ITS USES NanoSanguis S.A. (PL) 2026-05-21 WO claimed
EP-4744486-A1 PERFUSION FLUID, METHODS OF PRODUCING PERFUSION FLUID, AND ITS USES. NanoSanguis S.A. (PL) 2026-05-20 EP claimed
EP-4744487-A1 FLUID, METHODS OF PRODUCING FLUID, AND ITS USES NanoSanguis S.A. (PL) 2026-05-20 EP claimed
CN-122056850-A Broad-spectrum targeted virulence factor response type phototherapy nanoparticle, preparation method and application thereof in preparation of antibacterial drugs 温州医科大学 2026-05-19 CN claimed
US-12622812-B2 Otological surgery under perfluorocarbon liquids ALCON INC. (CH) 2026-05-12 US claimed
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-04-30 US claimed
EP-3458037-B1 FLUOROCHEMICAL TARGETED THERAPIES MTM RES LLC (US) 2026-04-29 EP claimed
EP-4717278-A1 NANOVECTORS FOR MAGNETIC RESONANCE IMAGING Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2026-04-01 EP claimed
EP-4704937-A1 DEVICE FOR THE ENTERAL ABSORPTION OF CO2, AND CORRESPONDING SET O11 biomedical GmbH (DE) 2026-03-11 EP claimed
EP-0231091-A1 Stable emulsions of highly fluorinated organic compound CHILDREN'S HOSPITAL MEDICAL CENTER (US) 1987-08-05 EP claimed
EP-0089232-B1 PERFLUOROCARBON LIQUIDS USEFUL IN EYE TREATMENT AND DIAGNOSTIC PROCEDURES CHILDREN'S HOSPITAL MEDICAL CENTER (US) 1986-07-02 EP claimed
US-4490351-A REPLACEMENT FOR VITREOUS AND AQUEOUS; TRANSPARENTIZES LENS AND CORNEA; SURGERY; MEDICAL DIAGNOSIS CHILDREN'S HOSPITAL MEDICAL CENTER (US) 1984-12-25 US claimed
EP-0112658-A2 Extraocular device for treating the eye CHILDREN'S HOSPITAL MEDICAL CENTER (US) 1984-07-04 EP claimed
US-4440745-A SKIN, DENTIFRICES, POLSHING; COPOLYMER OF POLYALKOXYSILANES AND A HYDROLYZABLE SILANE FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1984-04-03 US claimed
WO-1983003201-A1 METHODS OF TREATING THE EYE WITH LIQUID PERFLUOROCARBONS CHILDRENS HOSP MEDICAL CENTER (US) 1983-09-29 WO claimed
EP-0089232-A2 Perfluorocarbon liquids useful in eye treatment and diagnostic procedures CHILDREN'S HOSPITAL MEDICAL CENTER (US) 1983-09-21 EP claimed
US-4198287-A Method of regenerating coke-contaminated catalyst with simultaneous combustion of carbon monoxide UOP INC. (US) 1980-04-15 US claimed
US-4183962-A BIOLOGICALLY NONRETAINABLE LIQUID PERHALOCARBON EXXON RESEARCH & ENGINEERING CO. (US) 1980-01-15 US claimed
US-3951732-A Delignification and bleaching of wood pulp with oxygen in the presence of triethanolamine Osakeyhtio, A. Ahlstrom (SF) 1976-04-20 US claimed