Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31720936 | 1.00 | LMNA (1.00) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL2722025 | 1.00 | LMNA (1.00) | LMNATHRBCA2CA1MMP1 | |
| Perflubron SCHEMBL13724347 | 1.00 | LMNA (1.00) | LMNATHRBCA2CA1MMP1 | |
| Perflubrodec SCHEMBL364093 | 1.00 | LMNA (1.00) | LMNATHRBCA2CA1MMP1 | |
| Perflubron SCHEMBL33826 | 1.00 | LMNA (1.00) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL7029311 | 1.00 | LMNA (1.00) | LMNATHRBCA2CA1MMP1 | |
| Perflubron SCHEMBL8040555 | 1.00 | LMNA (1.00) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL4511229 | 1.00 | LMNA (1.00) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL249369 | 1.00 | LMNA (1.00) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL248644 | 1.00 | LMNA (1.00) | LMNATHRBCA2CA1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030044315-A1 | Method and device for the selective perfusion of fluids through blood vessels, controlled by the pressure in the blood vessels | BOEKSTEGERS PETER (DE) | 2003-03-06 | — | — | US | disclosed |
| US-6458323-B1 | Method and device for the vascular pressure-controlled selective perfusion of fluids through blood vessels | BOEKSTEGERS, PETER, DR. (DE) | 2002-10-01 | — | — | US | disclosed |