Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | QSOX1 | O00391 | 1/20 | 1.00 |
| ▸ | RGS12 | O14924 | 1/20 | 1.00 |
| ▸ | PMM2 | O15305 | 1/20 | 1.00 |
| ▸ | PLIN1 | O60240 | 1/20 | 1.00 |
| ▸ | GMNN | O75496 | 1/20 | 1.00 |
| ▸ | BBOX1 | O75936 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | CYBB | P04839 | 1/20 | 1.00 |
| ▸ | BCHE | P06276 | 1/20 | 1.00 |
| ▸ | GLA | P06280 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | G6PD | P11413 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ebselen SCHEMBL29370082 | 1.00 | METAP2 (1.00) | METAP2KDM4EMEN1QSOX1RGS12 | |
| Ebselen SCHEMBL4406056 | 1.00 | METAP2 (1.00) | METAP2KDM4EMEN1QSOX1RGS12 | |
| Ebselen SCHEMBL19064566 | 0.98 | METAP2 (0.96) | METAP2KDM4EMEN1QSOX1RGS12 | |
| Ebselen SCHEMBL20678555 | 0.98 | METAP2 (0.96) | METAP2KDM4EMEN1QSOX1RGS12 | |
| Ebselen SCHEMBL20477111 | 0.98 | METAP2 (0.96) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL193047 | 0.89 | METAP2 (0.79) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL28783439 | 0.87 | METAP2 (0.77) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL10501092 | 0.85 | METAP2 (1.00) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL10502294 | 0.85 | METAP2 (1.00) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL1354655 | 0.85 | METAP2 (0.74) | METAP2KDM4EMEN1QSOX1RGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 14182 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4228644-B1 | N-[4-[1-(1,4-DIOXASPIRO[4.5]DEC-8-YL)-4-(8-OXA-3-AZABICYCLO[3.2.1]OCT-3-YL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-6-YL]PHENYL]-N'-METHYLUREA FOR USE IN THE TREATMENT OF COVID19 | NANTCELL INC (US) | 2026-05-27 | — | — | EP | claimed |
| CN-122080099-A | Amphiphilic nicotinamide adenine dinucleotide conjugate, nano micelle and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| EP-3841097-B1 | 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER | BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) | 2026-05-20 | — | — | EP | claimed |
| EP-4744663-A2 | SKIN COMPOSITION | Eaderm Co., Ltd. (JP) | 2026-05-20 | — | — | EP | claimed |
| US-12628816-B2 | Storage solution including an aqueous culture medium and methods of preservation of live allografts | RESTORATION BIOLOGICS LLC (US) | 2026-05-19 | — | — | US | claimed |
| US-20260125650-A1 | METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES | TRAILHEAD BIOSYSTEMS INC (US) | 2026-05-07 | — | — | US | claimed |
| US-20260115231-A1 | TREATMENT OF CEREBRAL PALSY USING FIBROBLASTS | SPINALCYTE LLC (US) | 2026-04-30 | — | — | US | claimed |
| US-20260116861-A1 | ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS | THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) | 2026-04-30 | — | — | US | claimed |
| EP-4114975-B1 | FASCIN-2 (FSCN2) VARIANT AND USE THEREOF | REGENERON PHARMA (US) | 2026-04-29 | — | — | EP | claimed |
| EP-4725496-A2 | N-[4-[1-(1,4-DIOXASPIRO[4.5]DEC-8-YL)-4-(8-OXA-3-AZABICYCLO[3.2.1]OCT-3-YL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-6-YL]PHENYL]-N'-METHYLUREA FOR USE IN THE TREATMENT OF COVID19 | NantCell, Inc. (US) | 2026-04-15 | — | — | EP | claimed |
| EP-0354412-A2 | Process for the preparation of highly pure ebselene | A. Nattermann & Cie. GmbH (DE) | 1990-02-14 | — | — | EP | claimed |
| EP-0347927-A2 | Use of 2-phenyl-1,2-benzisoselenazol-3(2H)-one (ebselen) in the preparation of medicaments for the treatment of malaria | A. Nattermann & Cie. GmbH (DE) | 1989-12-27 | — | — | EP | claimed |
| EP-0296389-A1 | Pharmaceutical compositions with micronised Ebselen crystals | A. Nattermann & Cie. GmbH (DE) | 1988-12-28 | — | — | EP | claimed |
| US-4784994-A | Process for the treatment of inflammatory and allergic diseases | A. NATTERMANN & CIE GMBH (DE) | 1988-11-15 | — | — | US | claimed |
| US-4757063-A | Administering 2-phenyl-1,2-benzisoselenazol-3(2H)-one | A. NATTERMANN & CIE. GMBH (DE) | 1988-07-12 | — | — | US | claimed |
| EP-0249736-A2 | Ointment for the treatment of skin diseases | A. Nattermann & Cie. GmbH (DE) | 1987-12-23 | — | — | EP | claimed |
| EP-0249735-A2 | Pharmaceutical preparations comprising as active agent 2-phenyl-1.2-benzisoselenazol-3(2H)-one, for the treatment of diseases caused by oxidative stress | A. Nattermann & Cie. GmbH (DE) | 1987-12-23 | — | — | EP | claimed |
| EP-0044971-B1 | 2-PHENYL-1.2-BENZISOSELENAZOL-3(2H)-ONE CONTAINING PHARMACEUTICAL PREPARATIONS AND THEIR USE | A. Nattermann & Cie. GmbH (DE) | 1983-07-20 | — | — | EP | claimed |
| US-4352799-A | ANTISCLEROTIC, ANTIINFLAMMATORY | A. NATTERMANN & CIE GMBH (DE) | 1982-10-05 | — | — | US | claimed |
| EP-0044971-A1 | 2-Phenyl-1.2-benzisoselenazol-3(2H)-one containing pharmaceutical preparations and their use | A. Nattermann & Cie. GmbH (DE) | 1982-02-03 | — | — | EP | claimed |