Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 5/20 | 0.96 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.96 |
| ▸ | MEN1 | O00255 | 1/20 | 0.96 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.96 |
| ▸ | RGS12 | O14924 | 1/20 | 0.96 |
| ▸ | PMM2 | O15305 | 1/20 | 0.96 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.96 |
| ▸ | GMNN | O75496 | 1/20 | 0.96 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.96 |
| ▸ | LMNA | P02545 | 1/20 | 0.96 |
| ▸ | TP53 | P04637 | 1/20 | 0.96 |
| ▸ | CYBB | P04839 | 1/20 | 0.96 |
| ▸ | BCHE | P06276 | 1/20 | 0.96 |
| ▸ | GLA | P06280 | 1/20 | 0.96 |
| ▸ | POLB | P06746 | 1/20 | 0.96 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.96 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.96 |
| ▸ | MAPT | P10636 | 1/20 | 0.96 |
| ▸ | G6PD | P11413 | 1/20 | 0.96 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ebselen SCHEMBL4406056 | 0.98 | METAP2 (1.00) | METAP2KDM4EMEN1QSOX1RGS12 | |
| Ebselen SCHEMBL29370082 | 0.98 | METAP2 (1.00) | METAP2KDM4EMEN1QSOX1RGS12 | |
| Ebselen SCHEMBL33829 | 0.98 | METAP2 (1.00) | METAP2KDM4EMEN1QSOX1RGS12 | |
| Ebselen SCHEMBL20678555 | 0.96 | METAP2 (0.96) | METAP2KDM4EMEN1QSOX1RGS12 | |
| Ebselen SCHEMBL19064566 | 0.96 | METAP2 (0.96) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL193047 | 0.87 | METAP2 (0.79) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL28783439 | 0.85 | METAP2 (0.77) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL10501092 | 0.84 | METAP2 (1.00) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL30573251 | 0.84 | METAP2 (0.74) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL1354655 | 0.84 | METAP2 (0.74) | METAP2KDM4EMEN1QSOX1RGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024008788-A1 | USE OF EBSELEN OR ONE OF THE DERIVATIVES THEREOF TO TREAT MITOCHONDRIAL PATHOLOGIES OR DYSFUNCTIONS | ASSOCIATION FRANCAISE CONTRE LES MYOPATHIES (FR) | 2024-01-11 | — | — | WO | disclosed |
| US-11013730-B1 | Composition comprising selenazol or thiazalone derivatives and silver and method of treatment therewith | THIOREDOXIN SYSTEMS AB (SE) | 2021-05-25 | — | — | US | disclosed |
| US-10058542-B1 | Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith | THIOREDOXIN SYSTEMS AB (SE) | 2018-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11013730-B1 | Composition comprising selenazol or thiazalone derivatives and silver and method of treatment therewith | SELENOI, TST, SCLY | METAP2 1704/4885KDM4E 4710/4885MEN1 1564/4885 |
| US-10058542-B1 | Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith | SELENOI, TST, GSS | METAP2 2771/4885KDM4E 4515/4885MEN1 2291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.