SCHEMBL33833

SCHEMBL33833

c1ccc(-c2ncccn2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.62
RAB9A P51151 4/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
NFKB1 P19838 2/20 0.62
NFKB2 Q00653 2/20 0.62
RELA Q04206 2/20 0.62
MAPK1 P28482 1/20 0.58
CYP2A6 P11509 1/20 0.56
CLK4 Q9HAZ1 3/20 0.52
ADRB2 P07550 1/20 0.52
HPGDS O60760 6/20 0.48
NOTUM Q6P988 1/20 0.48
ALDH1A1 P00352 1/20 0.47
DYRK1A Q13627 1/20 0.46
POLB P06746 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
ADORA2A P29274 1/20 0.46
ADORA2B P29275 1/20 0.46
ADORA1 P30542 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28062294 1.00 NPC1 (0.62) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
Ammonia Solution, Strong SCHEMBL22446046 0.97 NPC1 (0.59) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
Biphenyl SCHEMBL9173025 0.97 RAB9A (0.67) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
Water SCHEMBL9051780 0.97 NPC1 (0.59) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
SCHEMBL2764106 0.97 NPC1 (0.59) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
SCHEMBL31538985 0.97 NPC1 (0.59) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
SCHEMBL3981949 0.97 NPC1 (0.59) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
SCHEMBL3157659 0.94 RAB9A (0.64) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
Pyridine SCHEMBL28854029 0.89 CYP2A6 (0.60) NPC1RAB9ASMN1; SMN2NFKB1NFKB2
SCHEMBL19009569 0.89 L3MBTL1 (0.56) NPC1RAB9ASMN1; SMN2NFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7236 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119735554-A Seed coating agent containing phenylpyrimidine compound and capable of promoting germination rate and seedling rate of seeds and application of seed coating agent 江苏里下河地区农业科学研究所 2025-04-01 CN claimed
US-12239010-B2 Light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2025-02-25 US claimed
CN-119219466-A Difluoro cyclobutane parallel ring compound, preparation method and application thereof 武汉大学 2024-12-31 CN claimed
EP-3805824-B1 IDENTIFICATION MEDIUM, AND METHOD FOR DETERMINING AUTHENTICITY OF IDENTIFICATION MEDIUM ZEON CORP (JP) 2024-10-09 EP claimed
CN-118307410-A Preparation method of chiral secondary alcohol compound 武汉大学 2024-07-09 CN claimed
EP-3356387-B1 ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS UNIV MONASH (AU) 2024-06-26 EP claimed
CN-115197203-B Aniline pyrimidine compound, preparation method and application thereof 上海医药工业研究院 2024-06-25 CN claimed
EP-3943492-B1 TADF MATERIALS COMPRISING 4-(3-(2-(10H-PHENOXAZIN-10-YL)PYRIDIN-5-YL)-9H-CARBAZOL-9-YL)BENZONITRILE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN OLEDS NOCTILUCA S A (PL) 2024-05-08 EP claimed
CN-117926356-A Nanocrystalline gold electroplating solution on surface of probe, preparation method and electroplating process 承盛航空测试科技(苏州)有限公司 2024-04-26 CN claimed
US-20240122179-A1 AUXINIC HERBICIDES AND METHODS OF USE THEREOF CORTEVA AGRISCIENCE LLC (US) 2024-04-18 US claimed
EP-0260077-A1 Phenyl pyrimidine compound and liquid crystalline composition AJINOMOTO CO., INC. (JP) 1988-03-16 EP claimed
EP-0055693-B1 USE OF PHENYL PYRIMIDINES AS PROTECTING AGENTS FOR CULTURE PLANTS AGAINST PHYTOTOXIC DAMAGE CAUSED BY HERBICIDES CIBA-GEIGY AG (CH) 1988-01-20 EP claimed
US-4698091-A 2-phenylpyrimidines, 2-naphthylpyrimidines and 2-heterocyclylpyrimidines as safeners for protecting cultivated plant against phytotoxic damage caused by herbicides CIBA-GEIGY CORPORATION (US) 1987-10-06 US claimed
EP-0225195-A1 Phenylpyrimidine-based compounds and liquid crystal composition containing the same AJINOMOTO CO., INC. (JP) 1987-06-10 EP claimed
EP-0136976-A2 Use of phenyl pyrimidines as plant regulators CIBA-GEIGY AG (CH) 1985-04-10 EP claimed
EP-0096657-A2 2-Phenyl-2-naphthyl and 2-heterocyclic pyrimidines as antidotes for protecting cultured plants before phytotoxic damages caused by herbicides CIBA-GEIGY AG (CH) 1983-12-21 EP claimed
US-4366080-A Liquid crystal display element TOKYO SHIBAURA DENKI KABUSHIKI KAISHA (JP) 1982-12-28 US claimed
US-4364838-A Liquid crystal mixtures HOFFMANN-LA ROCHE INC. (US) 1982-12-21 US claimed
EP-0055693-A1 Use of phenyl pyrimidines as protecting agents for culture plants against phytotoxic damage caused by herbicides CIBA-GEIGY AG (CH) 1982-07-07 EP claimed
EP-0032397-A1 Method of manufacturing a liquid crystal display SIEMENS AKTIENGESELLSCHAFT (DE) 1981-07-22 EP claimed