Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 8/20 | 0.44 |
| ▸ | KDR | P35968 | 10/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3383349 | 0.93 | FLT3 (0.47) | FLT3KDRFGFR3 | |
| SCHEMBL3386223 | 0.91 | FLT3 (0.43) | FLT3KDRFGFR3 | |
| SCHEMBL3386477 | 0.91 | KDR (0.47) | FLT3KDRFGFR3 | |
| SCHEMBL3385275 | 0.84 | KDR (0.51) | FLT3KDRFGFR3 | |
| SCHEMBL3385035 | 0.83 | KDR (0.49) | FLT3KDRFGFR3 | |
| SCHEMBL3382113 | 0.83 | KDR (0.50) | FLT3KDRFGFR3 | |
| SCHEMBL3381305 | 0.82 | KDR (0.46) | FLT3KDRFGFR3 | |
| SCHEMBL3381951 | 0.81 | FLT3 (0.58) | FLT3KDRFGFR3 | |
| SCHEMBL3380798 | 0.80 | FLT3 (0.49) | FLT3KDRFGFR3 | |
| SCHEMBL3385549 | 0.80 | KDR (0.47) | FLT3KDRFGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |