Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | EGFR | P00533 | 7/20 | 0.49 |
| ▸ | SRC | P12931 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30254999 | 0.81 | ALDH1A1 (0.73) | KDM4EALDH1A1EGFRSRCGAA | |
| SCHEMBL3382621 | 0.81 | ALDH1A1 (0.73) | KDM4EALDH1A1EGFRSRCGAA | |
| SCHEMBL11085961 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1EGFRSRCGAA | |
| SCHEMBL7964387 | 0.78 | KDM4E (0.53) | KDM4EALDH1A1EGFRSRCGAA | |
| SCHEMBL29942151 | 0.78 | CNR1 (0.54) | KDM4EALDH1A1 | |
| SCHEMBL2961716 | 0.78 | CNR1 (0.54) | KDM4EALDH1A1 | |
| SCHEMBL3069354 | 0.76 | KDM4E (0.68) | KDM4EALDH1A1HPGD | |
| SCHEMBL3228289 | 0.76 | CHRNB2 (0.67) | CHRNB2CHRNA7CHRNA4KDM4EALDH1A1 | |
| SCHEMBL30314130 | 0.75 | CHRNB2 (0.61) | CHRNB2CHRNA7CHRNA4KDM4EALDH1A1 | |
| SCHEMBL10965773 | 0.74 | KDM4E (0.52) | CHRNB2CHRNA7CHRNA4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149551-A1 | N-(indol-3-ylalkyl)-(hetero)arylamid derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | claimed |