Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3384408 | 0.91 | KDR (0.50) | KDRFGFR3 | |
| SCHEMBL3386487 | 0.86 | KDR (0.56) | KDRFGFR3 | |
| SCHEMBL3382628 | 0.82 | KDR (0.56) | KDRFGFR3 | |
| SCHEMBL3385504 | 0.82 | RAF1 (0.56) | KDRFGFR3 | |
| SCHEMBL3386460 | 0.82 | KDR (0.55) | KDRFGFR3 | |
| SCHEMBL3383255 | 0.82 | KDR (0.55) | KDRFGFR3 | |
| SCHEMBL3385521 | 0.81 | ALDH1A1 (0.55) | KDRFGFR3 | |
| SCHEMBL3385825 | 0.81 | FLT3 (0.51) | KDRFGFR3 | |
| SCHEMBL3383252 | 0.80 | KDR (0.69) | KDRFGFR3 | |
| SCHEMBL3383012 | 0.80 | KDR (0.63) | KDRFGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |