Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3383512 | 1.00 | CCR2 (0.44) | CCR2HSD17B10BTKSMN1; SMN2CYP1A2 | |
| SCHEMBL1266962 | 0.90 | CCR2 (0.44) | CCR2CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL2306832 | 0.90 | CCR2 (0.44) | CCR2CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL3384262 | 0.89 | CCR2 (0.45) | CCR2HSD17B10BTKSMN1; SMN2CYP1A2 | |
| SCHEMBL4311053 | 0.87 | BTK (0.48) | CCR2HSD17B10BTKSMN1; SMN2CYP1A2 | |
| SCHEMBL4311050 | 0.87 | BTK (0.48) | CCR2HSD17B10BTKSMN1; SMN2CYP1A2 | |
| SCHEMBL4311057 | 0.87 | BTK (0.48) | CCR2HSD17B10BTKSMN1; SMN2CYP1A2 | |
| SCHEMBL3420732 | 0.87 | CCR2 (0.42) | CCR2HSD17B10BTKSMN1; SMN2CYP1A2 | |
| SCHEMBL3382254 | 0.85 | CCR2 (0.39) | CCR2HSD17B10BTKSMN1; SMN2CYP1A2 | |
| SCHEMBL3382246 | 0.85 | CCR2 (0.39) | CCR2HSD17B10BTKSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140357651-A1 | COMBINATION PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | CALITHERA BIOSCIENCES, INC. | 2014-12-04 | — | — | US | disclosed |
| EP-2350060-B1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD (KR) | 2013-09-18 | — | — | EP | disclosed |
| US-8288386-B2 | Melanocortin receptor agonists | LG LIFE SCIENCES LTD. (KR) | 2012-10-16 | — | — | US | disclosed |
| US-8236955-B2 | Melanocortin receptor agonists | LG LIFE SCIENCES LTD. (KR) | 2012-08-07 | — | — | US | disclosed |
| US-8183243-B2 | Melanocortin receptor agonists | LG LIFE SCIENCES LTD. (KR) | 2012-05-22 | — | — | US | disclosed |
| WO-2010056022-A2 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2010-05-20 | — | — | WO | disclosed |
| US-20090298829-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2009-12-03 | — | — | US | disclosed |
| EP-2041120-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG Life Sciences Ltd. (KR) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008007930-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298829-A1 | MELANOCORTIN RECEPTOR AGONISTS | MC1R, MC3R, MC5R | CCR2 562/4885HSD17B10 1732/4885BTK 2320/4885 |
| US-20140357651-A1 | COMBINATION PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | CDC25C, CCNC, CDC25B | CCR2 2558/4885HSD17B10 970/4885BTK 3900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.