Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2363475 | 0.91 | CCR2 (0.42) | CCR2SMN1; SMN2POLBCYP1A2CYP3A4 | |
| SCHEMBL3383512 | 0.87 | CCR2 (0.44) | CCR2SMN1; SMN2HSD17B10BTKPOLB | |
| SCHEMBL3384307 | 0.87 | CCR2 (0.44) | CCR2SMN1; SMN2HSD17B10BTKPOLB | |
| SCHEMBL3384262 | 0.86 | CCR2 (0.45) | CCR2SMN1; SMN2HSD17B10BTKPOLB | |
| SCHEMBL4311053 | 0.84 | BTK (0.48) | CCR2SMN1; SMN2HSD17B10BTKPOLB | |
| SCHEMBL4311050 | 0.84 | BTK (0.48) | CCR2SMN1; SMN2HSD17B10BTKPOLB | |
| SCHEMBL4311057 | 0.84 | BTK (0.48) | CCR2SMN1; SMN2HSD17B10BTKPOLB | |
| SCHEMBL3382254 | 0.82 | CCR2 (0.39) | CCR2SMN1; SMN2HSD17B10BTKPOLB | |
| SCHEMBL3382246 | 0.82 | CCR2 (0.39) | CCR2SMN1; SMN2HSD17B10BTKPOLB | |
| SCHEMBL5133167 | 0.82 | CCR2 (0.39) | CCR2SMN1; SMN2HSD17B10BTKPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350060-B1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD (KR) | 2013-09-18 | — | — | EP | disclosed |
| WO-2010056022-A2 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2010-05-20 | — | — | WO | disclosed |