Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 3/20 | 0.75 |
| ▸ | ULK2 | Q8IYT8 | 3/20 | 0.75 |
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.59 |
| ▸ | CHEK1 | O14757 | 11/20 | 0.58 |
| ▸ | FLT3 | P36888 | 11/20 | 0.58 |
| ▸ | STK17B | O94768 | 2/20 | 0.57 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.56 |
| ▸ | KIT | P10721 | 3/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.56 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.56 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.56 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.56 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.56 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.56 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.56 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385882 | 0.97 | ULK1 (0.71) | ULK1ULK2STK17ACHEK1FLT3 | |
| SCHEMBL27087860 | 0.90 | ULK1 (0.73) | ULK1ULK2STK17ACHEK1FLT3 | |
| SCHEMBL29989851 | 0.90 | ULK1 (0.73) | ULK1ULK2STK17ACHEK1FLT3 | |
| SCHEMBL27087849 | 0.90 | ULK1 (0.73) | ULK1ULK2STK17ACHEK1FLT3 | |
| SCHEMBL3384590 | 0.87 | ULK1 (0.74) | ULK1ULK2CHEK1FLT3TBK1 | |
| SCHEMBL27402989 | 0.87 | ULK1 (0.72) | ULK1ULK2STK17ACHEK1FLT3 | |
| SCHEMBL29989356 | 0.87 | ULK1 (0.72) | ULK1ULK2STK17ACHEK1FLT3 | |
| SCHEMBL29990151 | 0.86 | ULK1 (0.71) | ULK1ULK2STK17ACHEK1FLT3 | |
| SCHEMBL27087794 | 0.86 | ULK1 (0.71) | ULK1ULK2STK17ACHEK1FLT3 | |
| SCHEMBL13431972 | 0.84 | ULK1 (1.00) | ULK1ULK2STK17ATBK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056524-A1 | Compound | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056524-A1 | Compound | NR3C2, NR3C1, NR2E3 | ULK1 2369/4885ULK2 1695/4885STK17A 381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.