Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL20668544 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL28062573 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL21555662 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL317585 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL3277654 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL23012792 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL20917176 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL15254602 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL20668546 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL5311584 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8308842-B2 | Pyrophoric iron nanoparticles and continuous processes for production thereof | XEROX CORPORATION (US) | 2012-11-13 | — | — | US | claimed |
| US-20120145947-A1 | PYROPHORIC IRON NANOPARTICLES AND CONTINUOUS PROCESSES FOR PRODUCTION THEREOF | XEROX CORPORATION (US) | 2012-06-14 | — | — | US | claimed |
| US-8308842-B2 | Pyrophoric iron nanoparticles and continuous processes for production thereof | XEROX CORPORATION (US) | 2012-11-13 | — | — | US | disclosed |
| US-20120208026-A1 | Silica-Coated Magnetic Nanoparticles and Process for Making Same | XEROX CORPORATION (US) | 2012-08-16 | — | — | US | disclosed |
| US-20120145947-A1 | PYROPHORIC IRON NANOPARTICLES AND CONTINUOUS PROCESSES FOR PRODUCTION THEREOF | XEROX CORPORATION (US) | 2012-06-14 | — | — | US | disclosed |
| US-8097185-B2 | Magnetic activated carbon particles for adsorption of solutes from solution | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2012-01-17 | — | — | US | disclosed |
| EP-1428228-A4 | MAGNETIC ACTIVATED PARTICLES FOR ADSORPTION OF SOLUTES FROM SOLUTION | UNIV UTAH RES FOUND (US) | 2008-04-30 | — | — | EP | disclosed |
| US-20040147397-A1 | a carbon precursor of soft wood is soaked in a solution of a ferric salt, dried, pyrolized and activated; waste water treatment; recovery of dissolved gold cyanide complexes and precious metals; fine particle size and homogeneous magnetism | MILLER JAN D (US) | 2004-07-29 | — | — | US | disclosed |
| EP-1428228-A1 | MAGNETIC ACTIVATED PARTICLES FOR ADSORPTION OF SOLUTES FROM SOLUTION | University of Utah Research Foundation (US) | 2004-06-16 | — | — | EP | disclosed |
| WO-2002069351-A1 | MAGNETIC ACTIVATED CARBON PARTICLES FOR ADSORPTION OF SOLUTES FROM SOLUTION | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2002-09-06 | — | — | WO | disclosed |