Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL20668544 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL28062573 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL21555662 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL3277654 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL338469 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL23012792 | 1.00 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL20917176 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL15254602 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL20668546 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL5311584 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 425 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026099311-A2 | MICROBIAL CELL FACTORIES PRODUCING PROSTAGLANDINS | RIVER STONE BIOTECH APS (DK) | 2026-05-15 | — | — | WO | claimed |
| US-20260071094-A1 | GUANIDINIUM-BASED POLYIONIC LIQUIDS AND THEIR USE AS ADDITIVES FOR CHEMICAL MECHANICAL PLANARIZATION SLURRIES | VERSUM MAT US LLC (US) | 2026-03-12 | — | — | US | claimed |
| EP-4594366-A1 | MODIFIED WATER-SOLUBLE POLYSACCHARIDES HAVING DIFFERENT CATION TYPES FOR SLURRIES IN CHEMICAL MECHANICAL PLANARIZATION | Versum Materials US, LLC (US) | 2025-08-06 | — | — | EP | claimed |
| US-20250215130-A1 | Polycationic Polymer Or Copolymer Having Different Cation Types For Slurries In Chemical Mechanical Planarization | MERCK PATENT GMBH (DE) | 2025-07-03 | — | — | US | claimed |
| WO-2025133859-A1 | CYCLIC IRON (II) CITRATE MONOHYDRATE AND PRODUCTION METHOD THEREOF, PHARMACEUTICAL AND/OR NUTRACEUTICAL AND/OR FOOD COMPOSITIONS COMPRISING IT AND USES THEREOF IN THERAPY AND IN THE NUTRITIONAL FIELD | TI. FARMA SRL (IT) | 2025-06-26 | — | — | WO | claimed |
| CN-120152997-A | Guanidine-based polymer liquid and its use as additive for chemical mechanical planarization slurries | 弗萨姆材料美国有限责任公司 | 2025-06-13 | — | — | CN | claimed |
| CN-119183462-A | Polycationic polymers or copolymers with different cation types for chemical mechanical planarization slurries | 默克专利有限公司 | 2024-12-24 | — | — | CN | claimed |
| CN-118370247-B | Method for improving survival rate of hong Kong giant oyster under high-salt condition | 北部湾大学 | 2024-12-10 | — | — | CN | claimed |
| US-20240400861-A1 | Triazole- And/Or Triazolium-Based Polymers And Copolymers As Additives For Chemical Mechanical Planarization Slurries | VERSUM MATERIALS US, LLC | 2024-12-05 | — | — | US | claimed |
| EP-4423796-A1 | POLISHING COMPOSITIONS AND METHODS OF USE THEREOF | FUJIFILM Electronic Materials U.S.A, Inc. (US) | 2024-09-04 | — | — | EP | claimed |
| EP-2871157-A1 | METHOD FOR PREPARING LITHIUM IRON PHOSPHATE NANOPOWDER | LG Chem, Ltd. (KR) | 2015-05-13 | — | — | EP | claimed |
| EP-2871160-A1 | METHOD FOR PREPARING LITHIUM IRON PHOSPHATE NANOPOWDER | LG Chem, Ltd. (KR) | 2015-05-13 | — | — | EP | claimed |
| EP-2871158-A1 | METHOD FOR PREPARING CARBON-COATED LITHIUM IRON PHOSPHATE NANOPOWDER | LG Chem, Ltd. (KR) | 2015-05-13 | — | — | EP | claimed |
| US-20150037666-A1 | METHOD FOR PREPARING LITHIUM IRON PHOSPHATE NANOPOWDER COATED WITH CARBON | LG CHEM, LTD. (KR) | 2015-02-05 | — | — | US | claimed |
| US-20150037665-A1 | METHOD FOR PREPARING LITHIUM IRON PHOSPHATE NANOPOWDER COATED WITH CARBON | LG CHEM, LTD. (KR) | 2015-02-05 | — | — | US | claimed |
| US-20150030918-A1 | METHOD FOR PREPARING LITHIUM IRON PHOSPHATE NANOPOWDER | LG CHEM, LTD. (KR) | 2015-01-29 | — | — | US | claimed |
| US-20150024265-A1 | METHOD FOR PREPARING LITHIUM IRON PHOSPHATE NANOPOWDER | LG CHEM, LTD. (KR) | 2015-01-22 | — | — | US | claimed |
| US-20150024271-A1 | METHOD FOR PREPARING LITHIUM IRON PHOSPHATE NANOPOWDER | LG CHEM, LTD. (KR) | 2015-01-22 | — | — | US | claimed |
| US-20150024266-A1 | METHOD FOR PREPARING LITHIUM IRON PHOSPHATE NANOPOWDER | LG CHEM, LTD. (KR) | 2015-01-22 | — | — | US | claimed |
| CN-104000791-A | Ferric citrate chewable tablet | ANHUI YI XIN MING PHARMACEUTICAL CO LTD | 2014-08-27 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260071094-A1 | GUANIDINIUM-BASED POLYIONIC LIQUIDS AND THEIR USE AS ADDITIVES FOR CHEMICAL MECHANICAL PLANARIZATION SLURRIES | SMG1, SRM, SMC3 | CA4 1059/4885ALDH1A1 1466/4885CASP1 1771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.