SCHEMBL3384779

SCHEMBL3384779

O=C(O)Cc1cccc(CCl)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 2/20 0.58
CYP1A2 P05177 1/20 0.49
CYP2C19 P33261 1/20 0.49
CA2 P00918 2/20 0.48
TSHR P16473 3/20 0.48
LMNA P02545 2/20 0.48
GAA P10253 2/20 0.48
KDM4E B2RXH2 2/20 0.48
MAPT P10636 2/20 0.48
HPGD P15428 2/20 0.48
HSD17B10 Q99714 2/20 0.48
RGS12 O14924 1/20 0.48
POLB P06746 1/20 0.48
NFKB1 P19838 1/20 0.48
APEX1 P27695 1/20 0.48
THPO P40225 1/20 0.48
BLM P54132 1/20 0.48
GNAI1 P63096 1/20 0.48
PMP22 Q01453 1/20 0.48
HIF1A Q16665 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70565 0.89 AKR1B1 (0.71) AKR1B1CYP1A2CYP2C19CA2TSHR
Hydrochloric Acid SCHEMBL8922940 0.87 AKR1B1 (0.68) AKR1B1CYP1A2CYP2C19CA2TSHR
SCHEMBL11257717 0.83 AKR1B1 (0.58) AKR1B1CYP1A2CYP2C19CA2TSHR
SCHEMBL4402323 0.83 AKR1B1 (0.62) AKR1B1CYP1A2CYP2C19CA2TSHR
Phenylacetic Acid SCHEMBL27805542 0.83 AKR1B1 (0.77) AKR1B1CA2TSHRLMNAGAA
SCHEMBL1401775 0.81 AKR1B1 (0.60) AKR1B1CYP1A2CYP2C19CA2TSHR
SCHEMBL19333997 0.80 KEAP1 (0.61) ALDH1A1KMT2A
SCHEMBL4557746 0.79 AKR1B1 (0.64) AKR1B1CYP1A2CYP2C19TSHRLMNA
SCHEMBL1515871 0.79 AKR1B1 (0.58) AKR1B1CYP1A2CYP2C19TSHRLMNA
SCHEMBL467923 0.79 CTBP2 (0.66) AKR1B1CA2LMNAHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118620977-A Preparation method of high-activity antibacterial peptide 安徽科技学院 2024-09-10 CN claimed
CN-115725678-A High-activity antibacterial peptide and preparation method thereof 吴丽萍 2023-03-03 CN claimed
CN-118620977-A Preparation method of high-activity antibacterial peptide 安徽科技学院 2024-09-10 CN disclosed
CN-115725678-A High-activity antibacterial peptide and preparation method thereof 吴丽萍 2023-03-03 CN disclosed
CN-115725678-A High-activity antibacterial peptide and preparation method thereof 吴丽萍 2023-03-03 CN disclosed
CN-109053443-A The bromo- 3- aldehyde radical-phenoxy group of 4-(4-)-benzonitrile synthetic method 杭州华东医药集团浙江华义制药有限公司 2018-12-21 CN disclosed
WO-2016202894-A1 METHOD OF CONVERTING ALCOHOL TO HALIDE UNIVERSITAET DES SAARLANDES (DE) 2016-12-22 WO disclosed
EP-1072580-B1 PROCESS FOR PRODUCING CHLOROMETHYLPHENYLACETIC ACID IHARA CHEMICAL IND CO (JP) 2010-12-01 EP disclosed
US-6414186-B1 REACTING METHYLPHENYLACETIC ACID WITH CHLORINE GAS, IN INERT SOLVENT, UNDER IRRADIATION WITH LIGHT OR IN PRESENCE OF RADICAL INITIATOR IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2002-07-02 US disclosed
EP-1072580-A1 PROCESS FOR PRODUCING CHLOROMETHYLPHENYLACETIC ACID Ihara Nikkei Chemical Industry Co., Ltd. (JP) 2001-01-31 EP disclosed
WO-2000037432-A1 METHOD OF PRODUCING AROMATIC HALOGEN METHYL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 2000-06-29 WO disclosed