⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27624069 | 0.72 | — | — | |
| SCHEMBL7359939 | 0.69 | — | — | |
| SCHEMBL8425651 | 0.69 | — | — | |
| SCHEMBL1195209 | 0.68 | — | — | |
| SCHEMBL10342488 | 0.67 | — | — | |
| SCHEMBL4684073 | 0.67 | — | — | |
| SCHEMBL9435821 | 0.67 | — | — | |
| SCHEMBL5142643 | 0.65 | TP53 (0.36) | — | |
| SCHEMBL7287488 | 0.65 | — | — | |
| SCHEMBL4686109 | 0.64 | CA2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103123671-B | The target gene Rv2780 for the treatment of tuberculosis inhibitor screening and application | HUAZHONG AGRICULTURAL UNIVERSITY (CN) | 2015-11-11 | — | — | CN | claimed |
| EP-1409497-B1 | METHOD FOR PREPARATION OF LNA PHOSPHORAMIDITES | SANTARIS PHARMA AS (DK) | 2005-01-19 | — | — | EP | claimed |
| EP-1409497-A2 | METHOD FOR PREPARATION OF LNA PHOSPHORAMIDITES | Santaris Pharma A/S (DK) | 2004-04-21 | — | — | EP | claimed |
| US-20030032794-A1 | Method for preparation of LNA phosphoramidites | SANTARIS PHARMA A/S (DK) | 2003-02-13 | — | — | US | claimed |
| WO-2003006475-A2 | METHOD FOR PREPARATION OF LNA PHOSPHORAMIDITES | SANTARIS PHARMA A/S (DK) | 2003-01-23 | — | — | WO | claimed |
| WO-1998016540-A1 | IMPROVED COUPLING ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS | PROLIGO LLC (US) | 1998-04-23 | — | — | WO | claimed |
| US-8193337-B2 | Oxidation process | AVECIA BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| US-20100137572-A1 | OXIDATION PROCESS | NITTO DENKO AVECIA, INC. | 2010-06-03 | — | — | US | disclosed |
| WO-2009007736-A1 | OXIDATION PROCESS | AVECIA BIOTECHNOLOGY INC. (US) | 2009-01-15 | — | — | WO | disclosed |
| US-7153954-B2 | Method for preparation of LNA phosphoramidites | SANTARIS PHARMA A/S (DK) | 2006-12-26 | — | — | US | disclosed |
| EP-1409497-B1 | METHOD FOR PREPARATION OF LNA PHOSPHORAMIDITES | SANTARIS PHARMA AS (DK) | 2005-01-19 | — | — | EP | disclosed |
| EP-1409497-A2 | METHOD FOR PREPARATION OF LNA PHOSPHORAMIDITES | Santaris Pharma A/S (DK) | 2004-04-21 | — | — | EP | disclosed |
| US-20030032794-A1 | Method for preparation of LNA phosphoramidites | SANTARIS PHARMA A/S (DK) | 2003-02-13 | — | — | US | disclosed |
| WO-2003006475-A2 | METHOD FOR PREPARATION OF LNA PHOSPHORAMIDITES | SANTARIS PHARMA A/S (DK) | 2003-01-23 | — | — | WO | disclosed |
| WO-1998016540-A1 | IMPROVED COUPLING ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS | PROLIGO LLC (US) | 1998-04-23 | — | — | WO | disclosed |
| WO-1998016540-A1 | IMPROVED COUPLING ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS | PROLIGO LLC (US) | 1998-04-23 | — | — | WO | disclosed |