Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 12/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 7/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | PPM1D | O15297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15414463 | 1.00 | SSTR4 (0.35) | SSTR4SSTR1HTR3AHTR4PPM1D | |
| SCHEMBL3384856 | 1.00 | SSTR4 (0.35) | SSTR4SSTR1HTR3AHTR4PPM1D | |
| SCHEMBL15414462 | 1.00 | SSTR4 (0.35) | SSTR4SSTR1HTR3AHTR4PPM1D | |
| SCHEMBL2691333 | 0.89 | SSTR4 (0.35) | SSTR4SSTR1HTR3AHTR4PPM1D | |
| SCHEMBL4444047 | 0.89 | SSTR4 (0.35) | SSTR4SSTR1HTR3AHTR4PPM1D | |
| SCHEMBL2691929 | 0.89 | SSTR4 (0.35) | SSTR4SSTR1HTR3AHTR4PPM1D | |
| SCHEMBL3877927 | 0.87 | PPM1D (0.32) | PPM1D | |
| SCHEMBL3877935 | 0.87 | PPM1D (0.32) | PPM1D | |
| SCHEMBL11978256 | 0.87 | GAA (0.36) | SSTR4SSTR1HTR3AHTR4 | |
| SCHEMBL15414426 | 0.87 | GAA (0.36) | SSTR4SSTR1HTR3AHTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120270864-A1 | 2-QUINOLINONE AND 2-QUINOXALINONE-DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB | 2012-10-25 | — | — | US | disclosed |
| US-20100144717-A1 | 2-QUINOLINONE AND 2-QUINOXALINONE-DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144717-A1 | 2-QUINOLINONE AND 2-QUINOXALINONE-DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | NQO2, SDHA, NDUFS5 | SSTR4 4719/4885SSTR1 4745/4885HTR3A 3006/4885 |
| US-20120270864-A1 | 2-QUINOLINONE AND 2-QUINOXALINONE-DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | NQO2, SDHA, NDUFS5 | SSTR4 4719/4885SSTR1 4745/4885HTR3A 3006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.