SCHEMBL3384898

SCHEMBL3384898

CC(c1ccccc1)c1ccccc1.N=C=O

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.41
MIF P14174 2/20 0.40
TYR P14679 1/20 0.39
TAAR1 Q96RJ0 3/20 0.39
ESR1 P03372 1/20 0.39
PDCD1 Q15116 1/20 0.39
ESR2 Q92731 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
KMT2A Q03164 1/20 0.38
CYP2D6 P10635 2/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2C P18825 1/20 0.38
LMNA P02545 1/20 0.38
HIF1A Q16665 1/20 0.38
KDM4E B2RXH2 1/20 0.38
SRC P12931 1/20 0.37
ALDH1A1 P00352 1/20 0.37
ALOX5 P09917 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132503 1.00 DAO (0.41) DAOMIFTYRTAAR1ESR1
SCHEMBL4808563 1.00 DAO (0.41) DAOMIFTYRTAAR1ESR1
Benzene SCHEMBL28319276 0.98 KMT2A (0.41) DAOMIFTYRTAAR1ESR1
Water SCHEMBL11440439 0.98 DAO (0.40) DAOMIFTYRTAAR1ESR1
Isopropylbenzene SCHEMBL133881 0.85 CYP2C9 (0.41) MIFTYRTAAR1CYP2D6ADRA2A
Isopropylbenzene SCHEMBL1347599 0.85 CYP2C9 (0.41) MIFTYRTAAR1CYP2D6ADRA2A
SCHEMBL28845471 0.84 ACP3 (0.47) DAOTYR
SCHEMBL7499823 0.84 TAAR1 (0.50) TYRTAAR1ESR1PDCD1ESR2
SCHEMBL169730 0.84 TAAR1 (0.50) TYRTAAR1ESR1PDCD1ESR2
Benzene SCHEMBL28192760 0.84 TAAR1 (0.50) TYRTAAR1ESR1PDCD1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111607053-B Thermoplastic polyurethane and molded article thereof 三晃股份有限公司 2022-06-07 CN disclosed
CN-112094206-A Bis (diphenylethane diisocyanate) propylene diester, preparation method and application 山东师范大学 2020-12-18 CN disclosed
CN-111607053-A Polyester diol, thermoplastic polyurethane and molded article thereof 三晃股份有限公司 2020-09-01 CN disclosed
CN-106458485-B Paper supply transport roller and its manufacturing method 新智德株式会社 2018-08-31 CN disclosed
EP-3178767-A1 PAPER FEED AND CONVEYANCE ROLL AND PRODUCTION METHOD THEREFOR Synztec Co., Ltd. (JP) 2017-06-14 EP disclosed
CN-106458485-A Paper feed and conveyance roll and production method therefor 新智德株式会社 2017-02-22 CN disclosed
US-20170021645-A1 ROLLER FOR FEEDING AND CONVEYING PAPER SHEETS AND METHOD FOR PRODUCING THE ROLLER SYNZTEC CO., LTD. (JP) 2017-01-26 US disclosed
US-8357522-B2 Separating material and method for collecting cell or the like using the same KANEKA CORPORATION (JP) 2013-01-22 US disclosed
US-20120322133-A9 SEPARATING MATERIAL AND METHOD FOR COLLECTING CELL OR THE LIKE USING THE SAME KANEKA CORPORATION (JP) 2012-12-20 US disclosed
US-20120156749-A1 SEPARATING MATERIAL AND METHOD FOR COLLECTING CELL OR THE LIKE USING THE SAME KANEKA CORPORATION (JP) 2012-06-21 US disclosed
EP-1260538-B1 PROCESS FOR PRODUCING POLYIMIDE RESIN KANEKA CORP (JP) 2010-12-01 EP disclosed
US-20090239300-A1 SEPARATING MATERIAL AND METHOD FOR COLLECTING CELL OR THE LIKE USING THE SAME KANEKA CORPORATION (JP) 2009-09-24 US disclosed
US-6790930-B1 FROM AN AROMATIC ACID DIANHYDRIDE AND A DIISOCYANATE OR AN AMINE; HYDROLYSIS PREVENTION; HIGH MOLECULAR WEIGHT; DRYING AND HEATING UNDER VACUUM; ONE STEP KANEKA CORPORATION (JP) 2004-09-14 US disclosed
EP-1260538-A1 PROCESS FOR PRODUCING POLYIMIDE RESIN Kaneka Corporation (JP) 2002-11-27 EP disclosed
EP-0222899-A4 TOOTH RESTORATION COMPOSITION, STRUCTURE AND METHODS. PORTEOUS DON D (US) 1989-02-09 EP disclosed
EP-0222899-A1 TOOTH RESTORATION COMPOSITION, STRUCTURE AND METHODS. PORTEOUS DON D (US) 1987-05-27 EP disclosed
WO-1986006957-A1 TOOTH RESTORATION COMPOSITION, STRUCTURE AND METHODS PORTEOUS DON D (US) 1986-12-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090239300-A1 SEPARATING MATERIAL AND METHOD FOR COLLECTING CELL OR THE LIKE USING THE SAME CD14, MYADM, CD68 DAO 2453/4885MIF 17/4885TYR 2894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.