Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666257 | 0.86 | PLAU (0.49) | PLAUALDH1A1KMT2AMAOBALOX15 | |
| SCHEMBL2747966 | 0.83 | PLAU (0.53) | PLAUALDH1A1KMT2AMAOBALOX15 | |
| SCHEMBL8395008 | 0.82 | PLAU (0.53) | PLAUALDH1A1KMT2AMAOBFFAR1 | |
| SCHEMBL29787368 | 0.82 | PLAU (0.53) | PLAUALDH1A1KMT2AMAOBFFAR1 | |
| SCHEMBL2747993 | 0.78 | KMT2A (0.45) | PLAUALDH1A1KMT2AMAOBMEN1 | |
| SCHEMBL12111157 | 0.76 | ALDH1A1 (0.48) | PLAUALDH1A1KMT2AMAOBALOX15 | |
| SCHEMBL31568528 | 0.75 | RAB9A (0.48) | PLAUALDH1A1KMT2AMAOBALOX15 | |
| SCHEMBL27320289 | 0.73 | TSHR (0.50) | PLAUALDH1A1KMT2AMAOBFFAR1 | |
| SCHEMBL9571372 | 0.72 | ALDH1A1 (0.49) | PLAUALDH1A1KMT2AMAOBALOX15 | |
| SCHEMBL8783073 | 0.70 | CDK4 (0.47) | ALDH1A1NPC1RAB9ATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036910-A1 | HEART PROTECTION BY ADMINISTERING AN AMP-ACTIVATED PROTEIN KINASE ACTIVATOR | OHTA YOSHIKAZU (JP) | 2010-04-01 | — | — | WO | disclosed |