Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385215 | 0.90 | TGFBR1 (0.38) | TGFBR1KMT2AADORA2AADORA1GPR119 | |
| SCHEMBL8871717 | 0.85 | POLB (0.48) | KMT2AADORA2AADORA1GPR119ALDH1A1 | |
| SCHEMBL30353336 | 0.84 | MERTK (0.39) | KMT2AADORA2AADORA1GPR119ALDH1A1 | |
| SCHEMBL28989766 | 0.84 | MERTK (0.39) | KMT2AADORA2AADORA1GPR119ALDH1A1 | |
| SCHEMBL8658906 | 0.82 | KMT2A (0.49) | TGFBR1KMT2AADORA2AADORA1GPR119 | |
| SCHEMBL31166291 | 0.80 | GPR119 (0.41) | TGFBR1KMT2AADORA2AADORA1GPR119 | |
| SCHEMBL5222977 | 0.76 | KMT2A (0.42) | TGFBR1KMT2AADORA2AADORA1GPR119 | |
| SCHEMBL6532552 | 0.72 | ADORA2A (0.52) | TGFBR1KMT2AADORA2AADORA1ALDH1A1 | |
| SCHEMBL8675020 | 0.72 | ADORA2A (0.46) | TGFBR1KMT2AADORA2AADORA1ALDH1A1 | |
| SCHEMBL8357453 | 0.70 | MERTK (0.43) | KMT2AALDH1A1HTTMEN1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149556-A1 | Method for manufacturing asymmetrical substituted dipyrazolyloxyphenyl derivatives | Bayer CropScience Aktiengesellschaft (DE) | 2010-02-03 | — | — | EP | disclosed |