Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385474 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EOPRL1MEN1KMT2A | |
| SCHEMBL3385636 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EOPRL1MEN1KMT2A | |
| SCHEMBL10913751 | 0.70 | KMT2A (0.54) | SMN1; SMN2KDM4EKMT2ACYP2D6CYP2C9 | |
| SCHEMBL8083108 | 0.69 | F2 (0.57) | MEN1KMT2ACYP2D6CYP2C9NPC1 | |
| Hydrochloric Acid SCHEMBL8843548 | 0.68 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EOPRL1NPC1RAB9A | |
| SCHEMBL20126634 | 0.68 | MEN1 (0.44) | OPRL1MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL14902519 | 0.68 | NPFFR1 (0.49) | SMN1; SMN2OPRL1MEN1KMT2ACYP3A4 | |
| SCHEMBL572327 | 0.67 | ALDH1A1 (0.62) | SMN1; SMN2KDM4EMEN1KMT2AATM | |
| SCHEMBL14902482 | 0.64 | KCNH2 (0.49) | SMN1; SMN2OPRL1MEN1KMT2ACYP3A4 | |
| SCHEMBL9020761 | 0.63 | HDAC6 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1864995-B1 | BETA-LACTAMIC RGD CYCLOPEPTIDES CONTAINING GAMMA TURNS | UNIV PAIS VASCO (ES) | 2010-12-08 | — | — | EP | disclosed |
| EP-1864995-A1 | BETA-LACTAMIC RGD CYCLOPEPTIDES CONTAINING GAMMA TURNS | UNIVERSIDAD DEL PAIS VASCO-EUSKAL HERRIKO UNIBERSITATEA (ES) | 2007-12-12 | — | — | EP | disclosed |