Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27484359 | 0.82 | MEN1 (0.51) | F2PRSS1KMT2AMEN1F10 | |
| SCHEMBL8913362 | 0.81 | F2 (0.47) | F2PRSS1KMT2AMEN1F10 | |
| SCHEMBL8913564 | 0.77 | F2 (0.44) | F2PRSS1KMT2AMEN1F10 | |
| SCHEMBL8082535 | 0.77 | KMT2A (0.40) | F2PRSS1KMT2APOLBCYP2D6 | |
| SCHEMBL8082537 | 0.77 | KMT2A (0.40) | F2PRSS1KMT2APOLBCYP2D6 | |
| SCHEMBL2311285 | 0.74 | ALDH1A1 (0.44) | KMT2APOLBCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2306405 | 0.73 | MMP1 (0.48) | KMT2APOLBCYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL27508550 | 0.73 | F2 (0.41) | F2PRSS1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8087931 | 0.71 | PPIA (0.51) | F2PRSS1KMT2APOLBCYP2D6 | |
| SCHEMBL4680616 | 0.71 | KDM1A (0.39) | F2PRSS1KMT2AMEN1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034215-A | 3-amino-2-oxo-1-piperidnercetic derivatives as enzyme inhibitors | CORVAS INTERNATIONAL, INC. (US) | 2000-03-07 | — | — | US | disclosed |
| US-5703208-A | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0802923-A1 | 3-AMINO-2-OXO-1-PIPERIDINEACETIC DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1997-10-29 | — | — | EP | disclosed |
| WO-1995035311-A9 | 3-AMINO-2-OXO-1-PIPERIDINEACETIC DERIVATIVES AS ENZYME INHIBITORS | — | 1996-02-01 | — | — | WO | disclosed |
| WO-1995035311-A1 | 3-AMINO-2-OXO-1-PIPERIDINEACETIC DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1995-12-28 | — | — | WO | disclosed |