SCHEMBL338552

SCHEMBL338552

[CH2]COc1ccc(C(C)(C)CCCCC)cc1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 19/20 0.49
CNR1 P21554 9/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10492948 0.86 NR5A1 (0.53) CNR2CNR1
SCHEMBL10513794 0.85 NR5A1 (0.56) CNR2CNR1
SCHEMBL988237 0.83 CNR2 (0.51) CNR2CNR1
SCHEMBL990538 0.82 CNR2 (0.54) CNR2CNR1
SCHEMBL7166616 0.81 CNR2 (0.53) CNR2CNR1
SCHEMBL4074135 0.81 CYP3A4 (0.62) CNR2CNR1
SCHEMBL4238919 0.81 CNR2 (0.47) CNR2CNR1
SCHEMBL2108030 0.81 CYP3A4 (0.54) CNR2CNR1
SCHEMBL1890228 0.80 CNR2 (0.47) CNR2CNR1
SCHEMBL1592413 0.80 CYP3A4 (0.53) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117883308-A Cosmetic or dermatological composition comprising a merocyanine and an oily phase comprising at least one alkyl or alkylene carbonate 莱雅公司 2024-04-16 CN disclosed
EP-4262719-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE CITRIC ACID ESTER L'OREAL (FR) 2023-10-25 EP disclosed
EP-4262714-A1 COSMETIC COMPOSITION COMPRISING A MEROCYANINE, A TRIAZINE UV-SCREENING AGENT, AND A POLYSACCHARIDE MODIFIED WITH HYDROPHOBIC CHAINS L'OREAL (FR) 2023-10-25 EP disclosed
US-11679069-B2 Cosmetic or dermatological composition comprising a merocyanine and an oily phase comprising at least one alkyl or alkylene carbonate L'OREAL (FR) 2023-06-20 US disclosed
WO-2022129059-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE CITRIC ACID ESTER L'OREAL (FR) 2022-06-23 WO disclosed
WO-2022129039-A1 COSMETIC COMPOSITION COMPRISING A MEROCYANINE, A TRIAZINE UV-SCREENING AGENT, AND A POLYSACCHARIDE MODIFIED WITH HYDROPHOBIC CHAINS L'OREAL (FR) 2022-06-23 WO disclosed
US-20210251868-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE ALKYL OR ALKYLENE CARBONATE L'OREAL (FR) 2021-08-19 US disclosed
EP-3827807-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE N-SUBSTITUTED AMIDE L'OREAL (FR) 2021-06-02 EP disclosed
US-11000460-B2 Cosmetic or dermatological composition comprising a merocyanine, an oily phase and a C1—C4 monoalkanol L'OREAL (FR) 2021-05-11 US disclosed
EP-3813779-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE ALKYL OR ALKYLENE CARBONATE L'OREAL SA (FR) 2021-05-05 EP disclosed
EP-1549283-A1 MEROCYANINE DERIVATIVES FOR COSMETIC USE Ciba SC Holding AG (CH) 2005-07-06 EP disclosed
WO-2005058269-A1 MEROCYANINE DERIVATIVES FOR COSMETIC USE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-06-30 WO disclosed
WO-2004085412-A2 SYMMETRICAL TRIAZINE DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-10-07 WO disclosed
US-20040191191-A1 Symmetrical triazine derivatives CIBA SPECIALTY CHEMICALS CORP. 2004-09-30 US disclosed
WO-2004052837-A2 AMINO SUBSTITUTED HYDROXYPHENYL BENZOPHENONE DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-24 WO disclosed
WO-2004006878-A1 MEROCYANINE DERIVATIVES FOR COSMETIC USE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-01-22 WO disclosed
US-4551420-A ULTRAVIOLET RAY ABSORBING POLYMER LATEX FUJI PHOTO FILM CO., LTD. (JP) 1985-11-05 US disclosed
US-4464462-A ULTRAVIOLET RAY-ABSORBING ACRYLIC POLYMER LATEX; ANTISTATIC AGENTS FUJI PHOTO FILM CO., LTD. (JP) 1984-08-07 US disclosed
US-4455368-A Silver halide photographic light-sensitive material containing a UV absorbing polymer latex FUJI PHOTO FILM CO., LTD. (JP) 1984-06-19 US disclosed
US-4443534-A VINYL CHLORIDE HOMO- OR COPOLYMER, OR ACRYLAMIDE OR ACRYLIC ESTER HOMO- OR COPOLYMER FUJI PHOTO FILM CO., LTD. (JP) 1984-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11679069-B2 Cosmetic or dermatological composition comprising a merocyanine and an oily phase comprising at least one alkyl or alkylene carbonate KRT18, DSG1, CUTA CNR2 2430/4885CNR1 2447/4885
US-20210251868-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN OILY PHASE COMPRISING AT LEAST ONE ALKYL OR ALKYLENE CARBONATE KRT18, DSC1, DSG1 CNR2 2138/4885CNR1 3012/4885
US-20040191191-A1 Symmetrical triazine derivatives H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, RNF168, CYC1 CNR2 2544/4885CNR1 1273/4885
US-11000460-B2 Cosmetic or dermatological composition comprising a merocyanine, an oily phase and a C1—C4 monoalkanol KRT18, C1S, C1R CNR2 2028/4885CNR1 1686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.