Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LGMN | Q99538 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3419080 | 0.91 | PTGFR (0.48) | PTGFRHSD11B1ALDH1A1HPGDMEN1 | |
| SCHEMBL3385965 | 0.84 | PTGFR (0.49) | PTGFRHSD11B1ALDH1A1HPGDPOLB | |
| SCHEMBL3384707 | 0.84 | PTGFR (0.51) | PTGFRHSD11B1ALDH1A1POLBATM | |
| SCHEMBL3386001 | 0.79 | PTGFR (0.55) | PTGFRHSD11B1ALDH1A1POLBTSHR | |
| SCHEMBL3384874 | 0.79 | PTGFR (0.59) | PTGFRHSD11B1ALDH1A1MMP2MMP9 | |
| SCHEMBL3381698 | 0.78 | PTGFR (0.47) | PTGFRHSD11B1ALDH1A1HPGDMMP2 | |
| SCHEMBL3381702 | 0.78 | PTGFR (0.47) | PTGFRHSD11B1ALDH1A1HPGDMMP2 | |
| SCHEMBL6885482 | 0.78 | PTGFR (0.51) | PTGFRHSD11B1ALDH1A1LGMNMMP2 | |
| SCHEMBL3383792 | 0.78 | PTGFR (0.58) | PTGFRHSD11B1ALDH1A1MMP2MMP9 | |
| SCHEMBL13005135 | 0.78 | PTGFR (0.58) | PTGFRHSD11B1ALDH1A1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487442-B1 | THIAZOLIDINE CARBOXAMIDE DERIVATIVES AS MODULATORS OF THE PROSTAGLANDIN F RECEPTOR | MERCK SERONO SA (CH) | 2010-12-01 | — | — | EP | claimed |